Chris Thomas

Prof

Accepting PhD Students

PhD projects

Chris Thomas is an internationally recognised authority on bacterial plasmid and mobile DNA and within the University has championed biotechnology. His current research focuses on:

Bacterial plasmids: Bacterial plasmids are important because of their role in spreading genes horizontally within bacterial populations and as tools for genetic manipulation. Professor Thomas's group has carried out detailed investigations of the genes which control DNA replication, plasmid segregation and conjugative transfer between dividing cells, including how they are regulated, with a view to help displace them in clinical and veterinary contexts but improve their properties as vectors.

Polyketide antibiotic biosynthesis: New antibiotics are required for use in medicine. The group is studying biosynthesis of mupirocin inPseudomonas fluorescenswith a view to generating new forms of this polyketide antibiotic that can be used against the superbug MRSA. It is also studying the biosynthesis of the related antibiotic thiomarinol in marine bacteria in order to understand how the additional elements of this antibiotic are made and how they increase the potency of the antibiotic compared to mupirocin.

1992 …2024

Research activity per year

Network

Sarah Batt

Person: Academic

Georgina Lloyd

Person: Academic

Scott White

Person: Academic

Tim Dafforn

Person: Academic

Paula Mendes

Person: Academic

Adam Cunningham

Person: Academic

Helen Cooper

Person: Academic

Alan McNally

  • Microbiology and Infection - Professor of Microbial Evolutionary Genomics, Institute Director in the Institute of Microbiology and Infection

Person: Academic

Sarah Conner

Person: Academic

Andrew Lovering

Person: Academic

Zhongshu Song

  • University of Bristol

External person

Thomas J Simpson

  • University of Bristol

External person

Christine L Willis

  • University of Bristol

External person

J Wu

  • Florida Atlantic University

External person

Russell J Cox

  • Institut Für Organische Chemie
  • Leibniz Universität Hannover
  • University of Bristol

External person

Matthew P Crump

  • University of Bristol

External person

Shu Shan Gao

  • University of Bristol

External person

Roberto La Ragione

  • University of Surrey

External person

John Crosby

  • University of Bristol

External person

Jonathan Iredell

  • University of Sydney

External person

Annabel C. Murphy

  • University of Bristol
  • Department of Biochemistry
  • University of Cambridge

External person

David Scott

  • University of Nottingham

External person

Manal AbuOun

  • Veterinary Laboratories Agency Weybridge
  • Animal and Plant Health Agency

External person

Muhammad Kamruzzaman

  • University of Sydney

External person

Rohit Farmer

  • Sam Higginbottom University of Agriculture, Technology and Sciences

External person

Rob Lavigne

  • KU Leuven

External person

Susan E. Jensen

  • University of Alberta

External person

Rohanah Hussain

  • Diamond Light Source

External person

Barrie Wilkinson

  • University of Melbourne
  • John Innes Centre

External person

Juan Pablo Gomez-Escribano

  • University of Melbourne
  • John Innes Centre

External person

Joanne M. Willey

  • Hofstra North Shore-Long Island Jewish School of Medicine

External person

Muriel Viaud

  • Unité BIOlogie et GEstion des Risques en Agriculture (BIOGER)
  • Unité Mixte de Recherche 1309 Contrôle des Maladies Animales Exotiques et Emergentes, Institut national de la recherche agronomique (INRA)

External person

Bohdan Ostash

  • Department of Genetics and Biotechnology
  • Ivan Franko National University of Lviv

External person

Jianhua Ju

  • Key Laboratory of Tropical Marine Bio-resources and Ecology
  • Guangdong Key Laboratory of Marine Materia Medica
  • RNAM Center for Marine Microbiology
  • South China Sea Institute of Oceanology
  • Chinese Academy of Sciences

External person

Tomohisa Kuzuyama

  • Biotechnology Research Center
  • Tokyo Metropolitan University

External person

Matthew Waldor

  • Harvard Medical School

External person

Jennifer Ritchie

  • University of Surrey

External person

Sean Doyle

  • Universidad del Valle
  • Maynooth University

External person

Pieter C. Dorrestein

  • University of California, San Diego
  • Center for Marine Biotechnology and Biomedicine
  • Scripps Institution of Oceanography
  • Collaborative Mass Spectrometry Innovation Center

External person

David P. Fewer

  • Microbiology and Biotechnology Division
  • Department of Food and Environmental Sciences
  • University of Helsinki

External person

Lena Gerwick

  • Center for Marine Biotechnology and Biomedicine
  • University of California, San Diego
  • Scripps Institution of Oceanography

External person

Alexey V. Melnik

  • University of California, San Diego

External person

Matthew L. Hillwig

  • University of Pittsburgh

External person

Wolfgang Wohlleben

  • German Centre for Infection Research (DZIF), Partner Site Tübingen
  • Microbiology/Biotechnology
  • Interfaculty Institute of Microbiology and Infection Medicine
  • Eberhard Karls University of Tübingen,

External person

Keishi Ishida

  • Leibniz Institute for Natural Product Research and Infection Biology (HKI)

External person

Yi Qiang Cheng

  • UNT System College of Pharmacy
  • University of North Texas Health Science Center

External person

Carmen Méndez

  • Departamento de Biología Funcional
  • Universidad de Oviedo
  • Instituto Universitario de Oncología Del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo

External person

Leonard Katz

  • Synthetic Biology Engineering Research Center (SynBERC)
  • University of California

External person

Renzo Kottmann

  • Microbial Genomics and Bioinformatics Research Group
  • Max Planck Institute for Marine Microbiology

External person

Irene De Bruijn

  • Netherlands Institute of Ecology

External person

Pelin Yilmaz

  • Microbial Genomics and Bioinformatics Research Group
  • Max Planck Institute for Marine Microbiology

External person

Hyun Uk Kim

  • Technical University of Denmark
  • BioInformatics Research Center
  • Korea Advanced Institute of Science and Technology (KAIST)

External person

Helge B. Bode

  • Merck Stiftungsprofessur Für Molekulare Biotechnologie
  • Johann Wolfgang Goethe-Universität Frankfurt
  • Fachbereich Biowissenschaften
  • Buchmann Institute for Molecular Life Sciences (BMLS)

External person

Axel A. Brakhage

  • Leibniz Institute for Natural Product Research and Infection Biology (HKI)

External person

CH Tuck

  • University of Nottingham
  • WRG

External person

Patrick Caffrey

  • University College Dublin

External person

Phillip Callow

  • Institut Laue-Langevin

External person

Brett A. Neilan

  • University of New South Wales

External person

Emily P. Balskus

  • Department of Chemistry and Chemical Biology
  • Harvard University

External person

Barry Scott

  • Vrije Universiteit Amsterdam
  • Massey University

External person

Yit Heng Chooi

  • Department of Chemical and Biomolecular Engineering
  • University of California
  • City University of New York
  • Georgia Institute of Technology
  • University of Western Australia

External person

Giuliano Siligardi

  • Diamond Light Source

External person

Guohui Pan

  • Scripps Research Institute

External person

Harald Gross

  • Eberhard Karls University of Tübingen,
  • German Centre for Infection Research (DZIF), Partner Site Tübingen

External person

Zhenhua Tian

  • State Key Laboratory of Bioorganic and Natural Products Chemistry
  • Chinese Academy of Sciences

External person

Elizabeth M H Wellington

  • University of Warwick

External person

Taifo Mahmud

  • Oregon State University

External person

Pablo Cruz-Morales

  • Evolution of Metabolic Diversity Laboratory
  • Unidad de Genómica Avanzada (Langebio)
  • Centro de Investigacion y de Estudios Avanzados

External person

Jean Luc Pernodet

  • Institute of Integrative Biology of the Cell (I2BC)
  • Commissariat À L'Energie Atomique (CEA)
  • Centre National de la Recherche Scientifique (CNRS)
  • IN2P3

External person

Federico Rosconi

  • Departamento de Bioquímica y Genómica Microbianas, IBCE

External person

Kapil Tahlan

  • Universidad del Valle
  • Memorial University of Newfoundland

External person

Kaarina Sivonen

  • Microbiology and Biotechnology Division
  • Department of Food and Environmental Sciences
  • University of Helsinki

External person

Sylvie Lautru

  • Institute of Integrative Biology of the Cell (I2BC)
  • Commissariat À L'Energie Atomique (CEA)
  • Centre National de la Recherche Scientifique (CNRS)
  • IN2P3

External person

Wilfred A. Van Der Donk

  • University of Illinois
  • Howard Hughes Medical Institute

External person

Ashley S Johnson-Rollings

  • University of Oxford

External person

Peter Timmins

  • Institut Laue-Langevin
  • Bristol Myers Squibb

External person

Christian Hertweck

  • Leibniz Institute for Natural Product Research and Infection Biology (HKI)
  • Friedrich Schiller University of Jena

External person

Evi Stegmann

  • German Centre for Infection Research (DZIF), Partner Site Tübingen
  • Microbiology/Biotechnology
  • Interfaculty Institute of Microbiology and Infection Medicine
  • Eberhard Karls University of Tübingen,

External person

Li Chen Han

  • University of Bristol

External person

Emily A. Monroe

  • Universidad del Valle
  • William Paterson University

External person

Jason Micklefield

  • University of Manchester

External person

Hyung Jin Kwon

  • Division of Bioscience and Bioinformatics
  • Myongji University

External person

Yunchang Xie

  • Key Laboratory of Tropical Marine Bio-resources and Ecology
  • Guangdong Key Laboratory of Marine Materia Medica
  • RNAM Center for Marine Microbiology
  • South China Sea Institute of Oceanology
  • Chinese Academy of Sciences

External person

Markus Nett

  • Leibniz Institute for Natural Product Research and Infection Biology (HKI)

External person

Daniel Petras

  • Technische Universitat Darmstadt
  • Technische Universität Berlin

External person

Anne Osbourn

  • John Innes Centre

External person

David Payne

  • GlaxoSmithKline
  • Imperial College London
  • Research Complex at Harwell

External person

William H Gaze

  • University of Warwick

External person

Daniel Krug

  • Helmholtz Institute for Pharmaceutical Research
  • Saarland University

External person

Sergey B. Zotchev

  • Department of Chemistry and Biotechnology
  • Norwegian University of Science and Technology

External person

Adam C. Jones

  • Gordon and Betty Moore Foundation

External person

John B. Biggins

  • Laboratory of Genetically Encoded Small Molecules
  • Albert Einstein College of Medicine
  • Rockefeller University

External person

Sean F. Brady

  • Laboratory of Genetically Encoded Small Molecules
  • Albert Einstein College of Medicine
  • Rockefeller University

External person

Shereen Shoma

  • University of Sydney

External person

Carla S. Jones

  • Sustainable Studies Program
  • Roosevelt University Chicago

External person

Ji'En Wu

  • University of Bristol
  • Institute of Molecular and Cell Biology, A-Star, Singapore

External person

Simon Carobene

  • University of Bristol

External person

David H. Sherman

  • Fudan University
  • Central Michigan University
  • Agency for Science, Technology and Research
  • University of Tampere

External person

Monika Ehling-Schulz

  • University of Veterinary Medicine Vienna

External person

Michael J. Smanski

  • University of Minnesota, Twin Cities

External person

Leonard Kaysser

  • Eberhard Karls University of Tübingen,
  • German Centre for Infection Research (DZIF), Partner Site Tübingen

External person

José A. Salas

  • Departamento de Biología Funcional
  • Universidad de Oviedo
  • Open University of Catalonia
  • Universitat Rovira i Virgili
  • Center for Cybersecurity Research of Catalonia

External person

Olivier Ploux

  • Laboratoire Interdisciplinaire des Energies de Demain (LIED)
  • UMR 8236 CNRS
  • Université Paris Denis Diderot

External person

Arnold J M Driessen

  • University of Melbourne
  • Groningen Biomolecular Sciences and Biotechnology Institute
  • Zernike Institute for Advanced Materials
  • University of Groningen

External person

Rainer Borriss

  • Fachbereich Phytomedizin
  • Albrecht Thaer Institut
  • Humboldt-Universität zu Berlin

External person

Frank Oliver Glöckner

  • Max Planck Institute for Marine Microbiology
  • Jacobs University
  • Alfred Wegener Institute

External person

Jon Clardy

  • Department of Biological Chemistry and Molecular Pharmacology
  • Harvard Medical School

External person

Karl Dieter Entian

  • Institute for Molecular Biosciences
  • Goethe University

External person

R. Cameron Coates

  • Department of Energy (DOE) Joint Genome Institute

External person

Gerard D Wright

  • Monash University
  • M.G. DeGroote Institute for Infectious Disease Research
  • McMaster University

External person

Rainer Breitling

  • Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM)
  • University of Manchester

External person

Jos M. Raaijmakers

  • Netherlands Institute of Ecology

External person

Andrew W. Truman

  • University of Melbourne
  • John Innes Centre

External person

Ben Shen

  • Scripps Research Institute
  • Molecular Therapeutics and Natural Products Library Initiative

External person

Julian I. Rood

  • Monash University

External person

Nicholas J. Tobias

  • Merck Stiftungsprofessur Für Molekulare Biotechnologie
  • Johann Wolfgang Goethe-Universität Frankfurt
  • Fachbereich Biowissenschaften

External person

Mikko Metsä-Ketelä

  • Department of Biochemistry
  • University of Turku

External person

Eriko Takano

  • Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM)
  • University of Manchester

External person

Anja Greule

  • Albert-Ludwigs-University of Freiburg

External person

Elizabeth Wyckoff

  • The University of Texas at Austin
  • Universidade Do Porto

External person

Ryan F. Seipke

  • University of Leeds

External person

Bradley S. Moore

  • University of California, San Diego
  • Center for Marine Biotechnology and Biomedicine
  • Scripps Institution of Oceanography

External person

Michalis Hadjithomas

  • Department of Energy (DOE) Joint Genome Institute

External person

Shelley M. Payne

  • The University of Texas at Austin
  • Universidade Do Porto

External person

Michael A. Fischbach

  • Department of Bioengineering and Therapeutic Sciences
  • University of California, San Francisco

External person

Davey L. Jones

  • Murdoch University
  • Bangor University

External person

William H. Gerwick

  • University of California, San Diego
  • Center for Marine Biotechnology and Biomedicine
  • Scripps Institution of Oceanography

External person

Simone M. Mantovani

  • Center for Marine Biotechnology and Biomedicine
  • University of California, San Diego
  • Scripps Institution of Oceanography

External person

J Davies

  • Winfrith Technology Centre
  • QinetiQ
  • Defence and Science Technology Laboratory

External person

Andriy Luzhetskyy

  • Helmholtz Institute for Pharmaceutical Research
  • Saarland University

External person

Roderich D. Süssmuth

  • Technische Universitat Darmstadt
  • Technische Universität Berlin

External person

Srikanth Duddela

  • Helmholtz Institute for Pharmaceutical Research
  • Saarland University

External person

Wen Liu

  • State Key Laboratory of Bioorganic and Natural Products Chemistry
  • Chinese Academy of Sciences

External person

Zhe Rui

  • Energy Biosciences Institute
  • University of California, Berkeley
  • Department of Chemical and Biomolecular Engineering

External person

Brendan F Gilmore

  • Queen's University, Belfast

External person

Maura di Martino

  • University of Warwick

External person

Jan Kormanec

  • Institute of Molecular Systems Biology
  • Slovak Academy of Sciences

External person

Nancy P. Keller

  • Harvard Medical School
  • University of Wisconsin-Madison
  • Department of Bacteriology

External person

Kai Blin

  • Technical University of Denmark

External person

Monica Höfte

  • Ghent University

External person

Oscar P Kuipers

  • Groningen Biomolecular Sciences and Biotechnology Institute
  • University of Groningen

External person

Leonilde M. Moreira

  • Institute for Bioengineering and Biosciences
  • Universidade de Lisboa

External person

Francisco Barona-Gómez

  • Evolution of Metabolic Diversity Laboratory
  • Unidad de Genómica Avanzada (Langebio)
  • Centro de Investigacion y de Estudios Avanzados

External person

Bertolt Gust

  • Eberhard Karls University of Tübingen,
  • German Centre for Infection Research (DZIF), Partner Site Tübingen

External person

Yi Tang

  • Department of Chemical and Biomolecular Engineering
  • University of California
  • City University of New York

External person

Laura Frost

  • University of Alberta

External person

Carl J. Balibar

  • Infectious Disease Research
  • Merck Research Laboratories

External person

Nathan Moss

  • Center for Marine Biotechnology and Biomedicine
  • University of California, San Diego
  • Scripps Institution of Oceanography

External person

Christopher T. Walsh

  • Engineering and Medicine for Human Health (ChEM-H) Institute
  • Stanford University

External person

Rolf Müller

  • Helmholtz Institute for Pharmaceutical Research
  • Saarland University
  • Helmholtz Center for Infection Research (HZI)

External person

Hans Wilhelm Nützmann

  • John Innes Centre

External person

Grazyna Jagura-burdzy

  • University of Birmingham

External person

Marnix H. Medema

  • Microbial Genomics and Bioinformatics Research Group
  • Max Planck Institute for Marine Microbiology
  • Bioinformatics Group
  • Wageningen University and Research Centre

External person

Xinyu Liu

  • University of Pittsburgh
  • National Engineering Research Center of Urban Environmental Pollution Control

External person

Carsten Kegler

  • Merck Stiftungsprofessur Für Molekulare Biotechnologie
  • Johann Wolfgang Goethe-Universität Frankfurt
  • Fachbereich Biowissenschaften

External person

Martin Woodward

  • University of Reading

External person

Grace Yim

  • Monash University
  • M.G. DeGroote Institute for Infectious Disease Research
  • McMaster University

External person

Mohamed S. Donia

  • Universitat de Barcelona
  • Princeton University

External person

Simon Foster

  • University of Sheffield

External person

Philipp Wiemann

  • Harvard Medical School
  • University of Wisconsin-Madison

External person

Bai Linquan

  • State Key Laboratory of Microbial Metabolism
  • Shanghai Jiao Tong University

External person

Douglas A. Mitchell

  • University of Illinois

External person

Christoph Geiger

  • Institute for Molecular Biosciences
  • Goethe University

External person

Alexander K. Apel

  • Eberhard Karls University of Tübingen,
  • German Centre for Infection Research (DZIF), Partner Site Tübingen

External person

Shaun Cawthraw

  • Animal and Plant Health Agency

External person

Peter Kötter

  • Institute for Molecular Biosciences
  • Goethe University

External person

A Prysor Williams

  • Bangor University

External person

Matthew Cummings

  • Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM)
  • University of Manchester

External person

Christopher A. Smith

  • University of Birmingham
  • Keele University

External person

P. Williams

  • Schering-Plough Animal Health

External person

Emma Laing

  • University of Surrey

External person

Fergal O'Gara

  • BIOMERIT Research Centre
  • Harvard Medical School
  • National University of Ireland
  • University of Cork
  • King’s College London
  • Curtin University

External person

Hideaki Oikawa

  • Fuel Cells and Solid State Chemistry Division
  • Kobe University
  • Hokkaido University

External person

Neha Garg

  • University of California, San Diego

External person

Chia Y. Lee

  • University of Tampere
  • University of Arkansas for Medical Sciences

External person

Marcus Moore

  • Universidad del Valle
  • Memorial University of Newfoundland

External person

Katrin Jungmann

  • Helmholtz Institute for Pharmaceutical Research
  • Saarland University

External person

Nikos C. Kyrpides

  • Department of Energy (DOE) Joint Genome Institute
  • University of Alberta
  • King Abdulaziz University

External person

Jonathan D. Walton

  • Department of Energy Great Lakes Bioenergy Research Center
  • Department of Energy Plant Research Laboratory
  • Michigan State University

External person

Jan Claesen

  • Department of Bioengineering and Therapeutic Sciences
  • University of California, San Francisco

External person

Martha Clokie

  • University of Leicester

External person

Fengan Yu

  • Fudan University
  • Central Michigan University
  • Agency for Science, Technology and Research
  • University of Tampere

External person

Brian V Jones

  • University of Brighton
  • Queen Victoria Hospital NHS Foundation Trust
  • University of Bath

External person

Eva Top

  • University of Idaho

External person

Yvonne Mast

  • Microbiology/Biotechnology
  • Interfaculty Institute of Microbiology and Infection Medicine
  • Eberhard Karls University of Tübingen,

External person

Aras Kadioglu

  • University of Liverpool

External person

Bertrand Aigle

  • Dynamique des Génomes et Adaptation Microbienne
  • Université de Lorraine and Institut National de la Recherche Agronomique (INRA)
  • Unité Mixte de Recherche (UMR) 1128

External person

Yuta Tsunematsu

  • Leibniz Institute for Natural Product Research and Infection Biology (HKI)
  • University of Shizuoka

External person

Jens Nielsen

  • Technical University of Denmark
  • Department of Chemical and Biological Engineering
  • Chalmers University of Technology

External person

K Lewis

  • Langford House
  • University of Bristol

External person

Andreas Bechthold

  • Albert-Ludwigs-University of Freiburg

External person

Celeste Brown

  • University of Idaho

External person

Sunil Shaunak

  • Imperial College London

External person

Marcia S. Osburne

  • Tufts University

External person

Kai Hilpert

  • St George Hosp

External person

Amrita Pati

  • Department of Energy (DOE) Joint Genome Institute

External person

Gilles P. Van Wezel

  • Molecular Biotechnology
  • Leiden University

External person

Diana Munera

  • Brigham & Womens Hosp

External person

Jörn Piel

  • ETH Zürich

External person

Irene Freire-Martin

  • University of Surrey

External person

Xiaohui Yan

  • Scripps Research Institute

External person

René De Mot

  • Centre of Microbial and Plant Genetics
  • Ghent University
  • KU Leuven

External person

Daniel J. Edwards

  • City University of New York
  • University of California

External person

F. Jerry Reen

  • BIOMERIT Research Centre
  • Harvard Medical School
  • National University of Ireland
  • University of Cork

External person

Sally Partridge

  • University of Sydney

External person

Tilmann Weber

  • Technical University of Denmark

External person

Miroslav Petricek

  • Academy of Sciences of Czech Republic

External person

Alistair B Boxall

  • University of York

External person

Jonathan L. Klassen

  • University of Aberdeen
  • University of Connecticut

External person

Changsheng Zhang

  • Key Laboratory of Tropical Marine Bio-resources and Ecology
  • Guangdong Key Laboratory of Marine Materia Medica
  • RNAM Center for Marine Microbiology
  • South China Sea Institute of Oceanology
  • Chinese Academy of Sciences

External person

Stephanie Düsterhus

  • Institute for Molecular Biosciences
  • Goethe University

External person

Nadine Ziemert

  • German Centre for Infection Research (DZIF), Partner Site Tübingen
  • Microbiology/Biotechnology
  • Interfaculty Institute of Microbiology and Infection Medicine
  • Eberhard Karls University of Tübingen,

External person