Chris Thomas

Prof

Accepting PhD Students

PhD projects

Chris Thomas is an internationally recognised authority on bacterial plasmid and mobile DNA and within the University has championed biotechnology. His current research focuses on:

Bacterial plasmids: Bacterial plasmids are important because of their role in spreading genes horizontally within bacterial populations and as tools for genetic manipulation. Professor Thomas's group has carried out detailed investigations of the genes which control DNA replication, plasmid segregation and conjugative transfer between dividing cells, including how they are regulated, with a view to help displace them in clinical and veterinary contexts but improve their properties as vectors.

Polyketide antibiotic biosynthesis: New antibiotics are required for use in medicine. The group is studying biosynthesis of mupirocin inPseudomonas fluorescenswith a view to generating new forms of this polyketide antibiotic that can be used against the superbug MRSA. It is also studying the biosynthesis of the related antibiotic thiomarinol in marine bacteria in order to understand how the additional elements of this antibiotic are made and how they increase the potency of the antibiotic compared to mupirocin.

1992 …2024

Research activity per year

Network

University of Bristol

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University of Birmingham

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University of Alberta

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University of Sydney

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University of Surrey

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Harvard Medical School

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Tufts University

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University of Pittsburgh

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Curtin University

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John Innes Centre

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UMR 8236 CNRS

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IN2P3

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Fudan University

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Royal Gwent Hospital

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University of Turku

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King Abdulaziz University

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Universidad del Valle

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Vrije Universiteit Amsterdam

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Rockefeller University

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Academy of Sciences of Czech Republic

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Leibniz Universität Hannover

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Kobe University

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Leiden University

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University of New South Wales

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Monash University

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University of Reading

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University of Arkansas for Medical Sciences

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Michigan State University

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Massey University

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University of Illinois

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University of Connecticut

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National University of Ireland

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Central Michigan University

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Jacobs University

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Japan Agency for Marine-Earth Science and Technology

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University of Idaho

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McMaster University

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Chinese Academy of Sciences

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University of California, Berkeley

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King’s College London

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University of Aberdeen

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Harvard University

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Technical University of Denmark

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University of Warwick

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University College Dublin

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Eberhard Karls University of Tübingen,

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Universitat de Barcelona

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Humboldt-Universität zu Berlin

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Technische Universität Berlin

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Ghent University

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Cardiff University

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University of Groningen

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University of Wisconsin-Madison

External organisation: No HESA Fund Source

Technische Universitat Darmstadt

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Myongji University

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Korea Advanced Institute of Science and Technology (KAIST)

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Albert Einstein College of Medicine

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University of California

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University of Nottingham

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National University of Singapore

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Hokkaido University

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University of Manchester

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University of California, San Diego

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Wageningen University and Research Centre

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Maynooth University

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Tokyo Metropolitan University

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KU Leuven

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Chalmers University of Technology

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Saarland University

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University of California, San Francisco

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University of Cambridge

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City University of New York

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Friedrich Schiller University of Jena

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University of Minnesota, Twin Cities

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Diamond Light Source

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Birmingham Heartlands Hospital

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Memorial University of Newfoundland

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Norwegian University of Science and Technology

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The University of Texas at Austin

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Universidade Do Porto

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Naicons Srl

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Sanger Ctr

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Université Paris Denis Diderot

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Sanger Inst

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Stanford University

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Brigham & Womens Hosp

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Universidade de Lisboa

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University of Leeds

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University of Veterinary Medicine Vienna

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University of Cork

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University of Melbourne

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Goethe University

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University of Western Australia

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Georgia Institute of Technology

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ETH Zürich

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Universidad de Oviedo

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University of Helsinki

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Shanghai Jiao Tong University

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Oregon State University

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Princeton University

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University of Tampere

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Novartis

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