Trivalent nanobody-based ligands mediate powerful activation of GPVI, CLEC-2 and PEAR1 in human platelets whereas FcγRIIA requires a tetravalent ligand

Eleyna Martin^*, Joanne Clark, Samantha Montague, Luis A Moran, Ying Di, Lily J Bull, Luke Whittle, Florije Raka, Richard Buka, Idrees Zafar, Caroline Kardeby, Alexandre Slater, Steve Watson^*

^*Corresponding author for this work

Cardiovascular Sciences

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The molecular basis of variation in response to platelet activation by FcgRIIA: implications for the risk of thrombosis
Nicolson, P., Watson, S., Cunningham, A. & Montague, S.
British Heart Foundation
17/07/23 → 16/07/26
Project: Research