SnapShot: Enveloped Virus Entry

Jason Mercer; Jeffrey E Lee; Erica Ollmann Saphire; Spencer A Freeman

doi:10.1016/j.cell.2020.06.033

SnapShot: Enveloped Virus Entry

Jason Mercer, Jeffrey E Lee, Erica Ollmann Saphire, Spencer A Freeman

Biosciences

Research output: Contribution to journal › Article › peer-review

Abstract

In order to initiate successful infection, viruses have to transmit and deliver their genome from one host cell or organism to another. To achieve this, enveloped viruses must first fuse their membrane with those of the target host cell. Here, we describe the sequence of events leading to the entry of representative enveloped viruses, highlighting the strategies they use to gain access to the host cell cytosol.

Original language	English
Pages (from-to)	786-786.e1
Journal	Cell
Volume	182
Issue number	3
DOIs	https://doi.org/10.1016/j.cell.2020.06.033
Publication status	Published - 6 Aug 2020

Bibliographical note

Keywords

Animals
Endocytosis
Endosomes/metabolism
Humans
Membrane Fusion
Virus Diseases/enzymology
Virus Internalization
Viruses/genetics

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10.1016/j.cell.2020.06.033

Cite this

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title = "SnapShot: Enveloped Virus Entry",

abstract = "In order to initiate successful infection, viruses have to transmit and deliver their genome from one host cell or organism to another. To achieve this, enveloped viruses must first fuse their membrane with those of the target host cell. Here, we describe the sequence of events leading to the entry of representative enveloped viruses, highlighting the strategies they use to gain access to the host cell cytosol.",

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AU - Lee, Jeffrey E

AU - Saphire, Erica Ollmann

AU - Freeman, Spencer A

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AB - In order to initiate successful infection, viruses have to transmit and deliver their genome from one host cell or organism to another. To achieve this, enveloped viruses must first fuse their membrane with those of the target host cell. Here, we describe the sequence of events leading to the entry of representative enveloped viruses, highlighting the strategies they use to gain access to the host cell cytosol.

KW - Animals

KW - Endocytosis

KW - Endosomes/metabolism

KW - Humans

KW - Membrane Fusion

KW - Virus Diseases/enzymology

KW - Virus Internalization

KW - Viruses/genetics

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DO - 10.1016/j.cell.2020.06.033

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VL - 182

SP - 786-786.e1

JO - Cell

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SnapShot: Enveloped Virus Entry

Abstract

Bibliographical note

Keywords

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