CuO nanoparticles as copper-ion reservoirs for Elesclomol-mediated intracellular oxidative stress: implications for anticancer therapies

Engineering & Materials Science

• Oxidative stress 100%
• Nanoparticles 56%
• Ions 52%
• Copper 46%
• Cell death 28%
• Cells 28%
• Dissolution 20%
• Reactive oxygen species 17%
• Density functional theory 14%
• Cytotoxicity 14%
• Cell culture 12%
• Metals 12%
• Isotopes 11%
• Molecular dynamics 10%
• Spectroscopy 10%
• Oxides 8%

Chemistry

• Elesclomol 99%
• Oxidative Stress 57%
• Nanoparticle 28%
• Cell Viability 19%
• Dissolution 14%
• Stable Isotope 10%
• Culture Media 10%
• Cell Death 10%
• Drug 10%
• Mammalian Cell 9%
• Reactive Oxygen Metabolite 9%
• Metal Oxide 7%
• Ion 7%
• Molecular Dynamics 7%
• Time 6%
• Spectroscopy 6%
• Density Functional Theory 5%
• Metal 4%