A cell-based, SARS-CoV-2 spike protein interaction assay to inform the neutralising capacity of recombinant and patient sera antibodies

Neale Harrison, Lauren Richardson, Chiara Pallini, Ines Morano, Elizabeth Jinks, Jamie Cowley, Hujo Chan, Harriet J. Hill, Aekkachai Tuekprakhon, Zhi Li, Cristina Matas de las Heras, Ana Teodosio, Andrea S. Lavado, Robert Moring, Ayesha Ashraf, Timothy R. Dafforn, Dimitris K. Grammatopoulos, John Gordon, Catherine A. Brady, Lawrence S. YoungNicholas M. Barnes, Zania Stamataki, Omar S. Qureshi^*

^*Corresponding author for this work

Pharmacy
Clinical Sciences
Immunology and Immunotherapy
Biosciences
Medical and Dental Sciences

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Development of a SARS-CoV-2 spike protein binding assay using human epithelial cells for COVID-19 therapy discovery and development
Willcox, B., Dafforn, T., Barnes, N. & Stamataki, Z.
TECHNOLOGY STRATEGY BOARD
1/01/21 → 30/06/22
Project: Other Government Departments

A cell-based, SARS-CoV-2 spike protein interaction assay to inform the neutralising capacity of recombinant and patient sera antibodies

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Development of a SARS-CoV-2 spike protein binding assay using human epithelial cells for COVID-19 therapy discovery and development