Yuk Ting Ma

2023

Bexmarilimab-induced macrophage activation leads to treatment benefit in solid tumors: The phase I/II first-in-human MATINS trial

Rannikko, J. H., Verlingue, L., De miguel, M., Pasanen, A., Robbrecht, D., Skytta, T., Iivanainen, S., Shetty, S., Ma, Y. T., Graham, D. M., Arora, S. P., Jaakkola, P., Yap, C., Xiang, Y., Mandelin, J., Karvonen, M. K., Jalkanen, J., Karaman, S., Koivunen, J. P., Minchom, A., & 2 othersHollmén, M. & Bono, P., 19 Dec 2023, In: Cell Reports Medicine. 4, 12, 101307.

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Immediate surgery compared with short-course neoadjuvant gemcitabine plus capecitabine, FOLFIRINOX, or chemoradiotherapy in patients with borderline resectable pancreatic cancer (ESPAC5): a four-arm, multicentre, randomised, phase 2 trial

Ghaneh, P., Palmer, D., Cicconi, S., Jackson, R., Halloran, C. M., Rawcliffe, C., Sripadam, R., Mukherjee, S., Soonawalla, Z., Wadsley, J., Al-Mukhtar, A., Dickson, E., Graham, J., Jiao, L., Wasan, H. S., Tait, I. S., Prachalias, A., Ross, P., Valle, J. W., O'Reilly, D. A., & 15 othersAl-Sarireh, B., Gwynne, S., Ahmed, I., Connolly, K., Yim, K-L., Cunningham, D., Armstrong, T., Archer, C., Roberts, K., Ma, Y. T., Springfeld, C., Tjaden, C., Hackert, T., Büchler, M. W. & Neoptolemos, J. P., Feb 2023, In: The Lancet Gastroenterology & Hepatology. 8, 2, p. 157-168 12 p.

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Textbook Outcome After Trans-arterial Chemoembolization for Hepatocellular Carcinoma

Mosconi, C., O’Rourke, J., Kloeckner, R., Sturm, L., Golfieri, R., Celsa, C., Fateen, W., Odisio, B. C., Garanzini, E. M., Peck-Radosavljevic, M., Borghi, A., Ma, Y. T., Stoehr, F., Bettinger, D., Giuffrida, P., Aithal, G. P., Lin, Y-M., Spreafico, C., Giampalma, E., Johnson, P., & 1 othersCucchetti, A., Apr 2023, In: Cardiovascular and Interventional Radiology. 46, 4, p. 449-459 11 p.

Research output: Contribution to journal › Article › peer-review

2022

Long-Term Outcomes and Exploratory Analyses of the Randomized Phase III BILCAP Study

BILCAP study group, 20 Jun 2022, In: Journal of Clinical Oncology . 40, 18, p. 2048-2057 10 p.

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Open Access

Phase I/II Multicenter Trial of a Novel Therapeutic Cancer Vaccine, HepaVac-101, for Hepatocellular Carcinoma

Löffler, M. W., Gori, S., Izzo, F., Mayer-Mokler, A., Ascierto, P. A., Königsrainer, A., Ma, Y. T., Sangro, B., Francque, S., Vonghia, L., Inno, A., Avallone, A., Ludwig, J., Alcoba, D. D., Flohr, C., Aslan, K., Mendrzyk, R., Schuster, H., Borrelli, M., Valmori, D., & 15 othersChaumette, T., Heidenreich, R., Gouttefangeas, C., Forlani, G., Tagliamonte, M., Fusco, C., Penta, R., Iñarrairaegui, M., Gnad-Vogt, U., Reinhardt, C., Weinschenk, T., Accolla, R. S., Singh-Jasuja, H., Rammensee, H-G. & Buonaguro, L., 15 Jun 2022, In: Clinical Cancer Research. 28, 12, p. 2555-2566 12 p.

Research output: Contribution to journal › Article › peer-review

2021

Association of gastric acid suppression and sorafenib efficacy in advanced hepatocellular carcinoma

Razak, R. A., Fletcher, P., Kunene, V. & Ma, Y. T., 28 Feb 2021, In: Journal of Clinical Gastroenterology. 55, 2, p. 169-173 5 p.

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Biopsy for advanced hepatocellular carcinoma: results of a multicentre UK audit

Childs, A., Zakeri, N., Ma, Y. T., O’Rourke, J., Ross, P., Hashem, E., Hubner, R. A., Hockenhull, K., Iwuji, C., Khan, S., Palmer, D. H., Connor, J., Swinson, D., Darby, S., Braconi, C., Roques, T., Yu, D., Luong, T. V. & Meyer, T., 9 Nov 2021, In: British Journal of Cancer. 125, 10, p. 1350-1355 6 p.

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Second-line FOLFOX chemotherapy versus active symptom control for advanced biliary tract cancer (ABC-06): a phase 3, open-label, randomised, controlled trial

Lamarca, A., Palmer, D. H., Wasan, H. S., Ross, P. J., Ma, Y. T., Arora, A., Falk, S., Gillmore, R., Wadsley, J., Patel, K., Anthoney, A., Maraveyas, A., Iveson, T., Waters, J. S., Hobbs, C., Barber, S., Ryder, W. D., Ramage, J., Davies, L. M., Bridgewater, J. A., & 1 othersValle, J. W., May 2021, In: The Lancet Oncology. 22, 5, p. 690-701 12 p.

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Systemic blockade of Clever-1 elicits lymphocyte activation alongside checkpoint molecule downregulation in patients with solid tumors: results from a phase I/II clinical trial

Virtakoivu, R., Rannikko, J. H., Viitala, M., Vaura, F., Takeda, A., Lönnberg, T., Koivunen, J., Jaakkola, P., Pasanen, A., Shetty, S., Jonge, M. J. A. D., Robbrecht, D., Ma, Y. T., Skyttä, T., Minchom, A., Jalkanen, S., Karvonen, M. K., Mandelin, J., Bono, P. & Hollmen, M., 2 Jun 2021, In: Clinical Cancer Research. 27, 15, p. 4205-4220

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The potential of PIVKA-II as a treatment response biomarker in hepatocellular carcinoma: a prospective United Kingdom cohort study

Sagar, V. M., Herring, K., Curbishley, S., Hodson, J., Fletcher, P., Karkhanis, S., Mehrzad, H., Punia, P., Shah, T., Shetty, S. & Ma, Y. T., 23 Nov 2021, In: OncoTarget. 12, 24, p. 2338-2350 13 p.

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The prognostic and diagnostic significance of the neutrophil-to-lymphocyte ratio in hepatocellular carcinoma: a prospective controlled study

Johnson, P. J., Dhanaraj, S., Berhane, S., Bonnett, L. & Ma, Y. T., 31 Aug 2021, In: British Journal of Cancer. 125, 5, p. 714-716 3 p.

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Upregulation of C/EBPα Inhibits Suppressive Activity of Myeloid Cells and Potentiates Antitumor Response in Mice and Patients with Cancer

Hashimoto, A., Sarker, D., Reebye, V., Jarvis, S., Sodergren, M. H., Kossenkov, A., Sanseviero, E., Raulf, N., Vasara, J., Andrikakou, P., Meyer, T., Huang, K-W., Plummer, R., Chee, C. E., Spalding, D., Pai, M., Khan, S., Pinato, D. J., Sharma, R., Basu, B., & 11 othersPalmer, D., Ma, Y-T., Evans, J., Habib, R., Martirosyan, A., Elasri, N., Reynaud, A., Rossi, J. J., Cobbold, M., Habib, N. A. & Gabrilovich, D. I., 1 Nov 2021, In: Clinical Cancer Research. 27, 21, p. 5961-5978 18 p.

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2020

MTL-CEBPA, a Small Activating RNA Therapeutic Up-Regulating C/EBP-α, in Patients With Advanced Liver Cancer: A First-In-Human, Multi-Centre, Open-Label, Phase I Trial

Ma, Y. T., May 2020, In: Clinical Cancer Research.

Research output: Contribution to journal › Article › peer-review

Recurrence patterns of pancreatic cancer after pancreatoduodenectomy: systematic review and a single-centre retrospective study

Kalisvaart, M., Broadhurst, D., Marcon, F., Pande, R., Schlegel, A., Sutcliffe, R., Marudanayagam, R., Mirza, D., Chatzizacharias, N., Abradelo, M., Muiesan, P., Isaac, J., Ma, Y. T., Mcconville, C. & Roberts, K., 8 Feb 2020, In: HPB : the official journal of the International Hepato Pancreato Biliary Association. 22, 9, p. 1240-1249

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Scheduling nab-paclitaxel combined with gemcitabine as first-line treatment for metastatic pancreatic adenocarcinoma

Corrie, P. G., Qian, W., Basu, B., Valle, J. W., Falk, S., Lwuji, C., Wasan, H., Scott-brown, M., Wadsley, J., Arif, S., Bridgewater, J., Propper, D., Gillmore, R., Gopinathan, A., Skells, R., Bundi, P., Brais, R., Dalchau, K., Bax, L., Chhabra, A., & 14 othersMachin, A., Dayim, A., Mcadam, K., Cummins, S., Wall, L., Ellis, R., Anthoney, A., Evans, J., Ma, Y. T., Isherwood, C., Neesse, A., Tuveson, D., Jodrell, D. I. & Palmer, D. H., 9 Jun 2020, In: British Journal of Cancer. 122, 12, p. 1760–1768 9 p.

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3 Citations (Scopus)

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TG01/GM-CSF and adjuvant gemcitabine in patients with resected RAS-mutant adenocarcinoma of the pancreas (CT TG01-01): a single-arm, phase 1/2 trial

Palmer, D. H., Valle, J. W., Ting Ma, Y., Faluyi, O., Neoptolemos, J. P., Jensen Gjertsen, T., Iversen, B., Amund Eriksen, J., Møller, A., Aksnes, A., Miller, R. & Dueland, S., 31 Mar 2020, In: British Journal of Cancer. 122, 7, p. 971–977 7 p.

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4 Citations (Scopus)

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Treatment strategies for the optimal management of locally advanced pancreatic adenocarcinoma with curative intent: A systematic review.

Ma, Y. T., 2020, In: Pancreas.

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1 Citation (Scopus)

2019

Capecitabine compared with observation in resected biliary tract cancer (BILCAP): a randomised, controlled, multicentre, phase 3 study

BILCAP study group, Primrose, J. N., Fox, R. P., Palmer, D. H., Malik, H. Z., Prasad, R., Mirza, D., Anthony, A., Corrie, P., Falk, S., Finch-Jones, M., Wasan, H., Ross, P., Wall, L., Wadsley, J., Evans, J. T. R., Stocken, D., Praseedom, R., Ma, Y. T., Davidson, B., & 9 othersNeoptolemos, J. P., Iveson, T., Raftery, J., Zhu, S., Cunningham, D., Garden, O. J., Stubbs, C., Valle, J. W. & Bridgewater, J., May 2019, In: The Lancet Oncology. 20, 5, p. 663-673 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

243 Citations (Scopus)

Development and validation of a risk score to predict the overall survival following surgical resection of hepatocellular carcinoma in non-cirrhotic liver

Dasari, B. V. M. & Ma, Y. T., 12 Aug 2019, (E-pub ahead of print) In: HPB : the official journal of the International Hepato Pancreato Biliary Association.

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Impact of intensified chemotherapy in metastatic pancreatic ductal adenocarcinoma (PDAC) in clinical routine in Europe.

Ahsan Javed, M. & Ma, Y. T., Jan 2019, In: Pancreatology. 19, 1, p. 97-104

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Patterns of Recurrence After Resection of Pancreatic Ductal Adenocarcinoma: A Secondary Analysis of the ESPAC-4 Randomized Adjuvant Chemotherapy Trial

Ma, Y. T., Nov 2019, In: JAMA Surgery.

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

2018

A multicentre, open-label, phase-I/randomised phase-II study to evaluate safety, pharmacokinetics, and efficacy of Nintedanib vs. Sorafenib in European patients with advanced hepatocellular carcinoma

Palmer, D. H., Ma, Y., Peck-Radosavljevic, M., Ross, P., Graham, J., Fartoux, L., Deptala, A., Studeny, M., Schnell, D., Hocke, J., Loembe, A-B. & Meyer, T., 22 Mar 2018, In: British Journal of Cancer. 118, p. 1162-1168 7 p.

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9 Citations (Scopus)

224 Downloads (Pure)

Non-secretion of AFP and neutrophil lymphocyte ratio as predictors for survival in hepatocellular carcinoma patients treated with sorafenib: a large UK cohort

Afshar, M., Fletcher, P., Bardoli, A., Ma, Y. & Punia, P., 30 Mar 2018, In: OncoTarget. 9, 24, p. 16988–16995 8 p.

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5 Citations (Scopus)

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Phase II studies with Refametinib or Refametinib plus Sorafenib in patients with RAS-mutated Hepatocellular Carcinoma

Lim, H. Y., Merle, P., Weiss, K-H., Yau, T. CC., Ross, P., Blanc, J-F., Mazzaferro, V., Ma, Y., Yen, C-J., Kocsis, J., Choo, S. P., Sukeepaisarnjaroen, W., Gérolami, R., Dufour, J-F., Gane, E. J., Ryoo, B-Y., Peck-Radosavljevic, M., Dao, T., Yeo, W., Lamlertthon, W., & 7 othersThongsawat, S., Teufel, M., Roth, K., Reis, D., Childs, B. H., Krissel, H. & Llovet, J. M., 27 Jun 2018, (E-pub ahead of print) In: Clinical Cancer Research.

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26 Citations (Scopus)

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The impact of transarterial chemoembolization induced complications on outcomes after liver transplantation: A propensity-matched study

Pinter Carvalheiro da Silva Boteon, A., Longatto Boteon, Y., Vinuela, E. F., Derosas, C., Mergental, H., Isaac, J. R., Muiesan, P., Mehzard, H., Ma, Y., Shah, T., Mirza, D. F. & Perera, M. T. P. R., May 2018, In: Clinical transplantation. 32, 5, 10 p., e13255.

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

2017

Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial

Neoptolemos, J. P., Palmer, D. H., Ghaneh, P., Psarelli, E. E., Valle, J. W., Halloran, C. M., Faluyi, O., O'Reilly, D. A., Cunningham, D., Wadsley, J., Darby, S., Meyer, T., Gillmore, R., Anthoney, A., Lind, P., Glimelius, B., Falk, S., Izbicki, J. R., Middleton, G., Cummins, S., & 15 othersRoss, P. J., Wasan, H., McDonald, A., Crosby, T., Ma, Y., Patel, K., Sherriff, D., Soomal, R., Borg, D., Sothi, S., Hammel, P., Hackert, T., Jackson, R., Büchler, M. W. & European Study Group for Pancreatic Cancer, 11 Mar 2017, In: The Lancet. 389, 10073, p. 1011–1024

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771 Citations (Scopus)

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Exceptional serological and radiological response to sorafenib in 2 patients with advanced hepatocellular carcinoma and chronic hepatitis C viral infection: case report and review of the literature

Atkin, C., Earwaker, P., Pallan, A., Shetty, S., Punia, P. & Ma, Y., 14 Feb 2017, In: BMC Gastroenterology. 17, 30.

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Prognostic scores for sorafenib-treated hepatocellular carcinoma patients: A new application for the hepatoma arterial embolisation prognostic score

Edeline, J., Blanc, J-F., Campillo-Gimenez, B., Ma, Y., King, J., Faluyi, O., Mathurin, J., Ghazi, S., Palmer, D. H. & Meyer, T., Nov 2017, In: European Journal of Cancer. 86, p. 135-142 8 p.

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Sorafenib in combination with transarterial chemoembolisation in patients with unresectable hepatocellular carcinoma (TACE 2): a randomised placebo-controlled, double-blind, phase 3 trial

Meyer, T., Fox, R., Ma, Y., Ross, P., James, M., Sturgess, R., Stubbs, C., Stocken, D., Wall, L., Watkinson, A., Hacking, N., Evans, J., Collins, P., Hubner, R., Cunningham, D., Primrose, J., Johnson, P. & Palmer, D., Aug 2017, In: The Lancet Gastroenterology & Hepatology. 2, 8, p. 565–575

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164 Citations (Scopus)

178 Downloads (Pure)

Use of a genome-wide haploid genetic screen to identify treatment predicting factors: a proof-of-principle study in pancreatic cancer.

Ma, Y., Leonard, S., Gordon, N., Anderton, J., James, C., Huen, D., Woodman, C. & Palmer, D. H., 8 Sept 2017, In: OncoTarget. 8, 38, p. 63635–63645 11 p.

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1 Citation (Scopus)

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2016

A multicentre comparison between Child Pugh and Albumin-Bilirubin scores in patients treated with sorafenib for Hepatocellular Carcinoma

Edeline, J., Blanc, J-F., Johnson, P., Campillo-Gimenez, B., Ross, P., Ma, Y., King, J., Hubner, R. A., Sumpter, K., Darby, S., Evans, J., Iwuji, C., Swinson, D., Collins, P., Patel, K., Muazzam, I., Palmer, D. H. & Meyer, T., Dec 2016, In: Liver International. 36, 12, p. 1821-1828 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

52 Citations (Scopus)

2015

Developments in cancer vaccines for hepatocellular carcinoma

Buonaguro, L., HEPAVAC Consortium, Ma, Y. & Adams, D., 21 Jun 2015, In: Cancer Immunology Immunotherapy. 65, 93.

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

2013

Sorafenib for advanced hepatocellular carcinoma (HCC): impact of rationing in the United Kingdom

Palmer, D. H., Hussain, S. A., Smith, A. J., Hargreaves, S., Ma, Y., Hull, D., Johnson, P. J. & Ross, P. J., 20 Aug 2013, In: British Journal of Cancer. 109, 4, p. 888-90 3 p.

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

2012

Impact of restricting access to high-cost medications for hepatocellular carcinoma

Ma, Y. T. & Palmer, D. H., 2012, In: Expert Review of Pharmacoeconomics & Outcomes Research. 12, 4, p. 465-73 9 p.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

2011

Biology of germ cell tumors.

Ma, Y., Cullen, M. & Hussain, S., 1 Jun 2011, In: Hematology/oncology clinics of North America. 25, 3, p. 457-71 15 p.

Research output: Contribution to journal › Article

7 Citations (Scopus)

Metastatic serous carcinoma of the testis: a case report and review of the literature

Ma, Y., Chaudhri, S. & Cullen, M., 1 Jan 2011, In: Case reports in oncology. 4, 1, p. 246-9 4 p.

Research output: Contribution to journal › Article

Open Access

Smoking initiation is followed by the early acquisition of epigenetic change in cervical epithelium: a longitudinal study.

Ma, Y., Collins, S., Young, L., Murray, P. & Woodman, C., 26 Apr 2011, In: British Journal of Cancer. 104, 9, p. 1500-4 5 p.

Research output: Contribution to journal › Article

35 Citations (Scopus)

2008

Biology of testicular germ cell tumors.

Hussain, S., Ma, Y., Palmer, D., Hutton, P. & Cullen, M., 1 Oct 2008, In: Expert Review of Anticancer Therapy. 8, 10, p. 1659-73 15 p.

Research output: Contribution to journal › Article

16 Citations (Scopus)

Management of metastatic germ cell tumors.

Hussain, S., Ma, Y. & Cullen, M., 1 May 2008, In: Expert Review of Anticancer Therapy. 8, 5, p. 771-84 14 p.

Research output: Contribution to journal › Article

18 Citations (Scopus)

2003

Facial flushing and localised Castleman's disease: An extension of the POEMS syndrome phenotype

Ma, Y., Weatherby, SJ., Rao, D., Winer, J., Craddock, C. & Williams, A., 1 Feb 2003, In: Journal of Internal Medicine. 253, 2, p. 247-248 2 p.

Research output: Contribution to journal › Article

1 Citation (Scopus)

Yuk Ting Ma

Research output

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