Elizabeth Sapey – Network — University of Birmingham

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Accepting PhD Students

PhD projects

Liz’s research interests focus on understanding why chronic inflammatory diseases are so heterogeneous in their presentation and course. The research includes two interrelated themes:

1. The role of innate immunity in disease pathogenesis, especially its role in tissue damage during ageing, chronic lung disease (COPD) and acute lung infections (primarily pneumonia). Aberrant neutrophil functions have been implicated in the tissue damage and poor bacterial clearance seen in each of these areas. She has focused on how neutrophil behaviour (and cell signalling) in the presence of inflammation alters in health and disease, in particular, how inaccurate migration and reduced phagocytosis lead to increased inflammatory burden and poorer clinical outcomes.

2. The need to characterise clinical and inflammatory phenotypes in frailty ageing, and chronic disease to better inform therapeutic targeting. This work includes studying how disease manifests in its most early stages, assessing physiological techniques that better diagnose both disease and decline, understanding the shared risk from other chronic inflammatory co-morbidities and utilising outcome measures that reflect pathology.

Research activity per year

The University of Birmingham

Organisational unit: University

162 shared research output

Medical and Dental Sciences

The University of Birmingham

Organisational unit: College

162 shared research output

Clinical Sciences

Medical and Dental Sciences

Organisational unit: School

50 shared research output

Birmingham Medical School

Clinical Sciences

Organisational unit: Department

34 shared research output

Immunology and Immunotherapy

Medical and Dental Sciences

Organisational unit: School

30 shared research output

Applied Health Research

Medical and Dental Sciences

Organisational unit: School

26 shared research output

Cardiovascular Sciences

Medical and Dental Sciences

Organisational unit: School

22 shared research output

Life and Environmental Sciences

The University of Birmingham

Organisational unit: College

14 shared research output

Cancer and Genomic Sciences

Medical and Dental Sciences

Organisational unit: School

9 shared research output

Sport, Exercise and Rehabilitation Sciences

Life and Environmental Sciences

Organisational unit: School

8 shared research output

Engineering and Physical Sciences

The University of Birmingham

Organisational unit: College

7 shared research output

Metabolism and Systems Research

Medical and Dental Sciences

Organisational unit: School

5 shared research output

Computer Science

Engineering and Physical Sciences

Organisational unit: School

5 shared research output

Health Economics Unit

Applied Health Research

Organisational unit: Unit

4 shared research output

Psychology

Life and Environmental Sciences

Organisational unit: School

4 shared research output

Dentistry

Clinical Sciences

Organisational unit: Department

3 shared research output

Biosciences

Life and Environmental Sciences

Organisational unit: School

3 shared research output

Arts and Law

The University of Birmingham

Organisational unit: College

2 shared research output

Theology and Religion

Philosophy, Theology and Religion

Organisational unit: Department

2 shared research output

Physiotherapy

Sport, Exercise and Rehabilitation Sciences

Organisational unit: Department

2 shared research output

Philosophy, Theology and Religion

Organisational unit: School

2 shared research output

Biomedical Sciences

Clinical Sciences

Organisational unit: Department

2 shared research output

Social Sciences

The University of Birmingham

Organisational unit: College

2 shared research output

Institute of Translational Medicine

Medical and Dental Sciences

Organisational unit: School

1 shared research output

Nursing and Midwifery

Clinical Sciences

Organisational unit: Department

1 shared research output

Government

Social Sciences

Organisational unit: School

1 shared research output

Electronic, Electrical and Systems Engineering

Organisational unit: Department

1 shared research output

Public Administration and Policy

Organisational unit: Department

1 shared research output

The Institute for Mental Health

Organisational unit: Institute

1 shared research output

The Centre of Precision Rehabilitation for Spinal Pain

Sport, Exercise and Rehabilitation Sciences

Organisational unit: Centre

1 shared research output

Birmingham Business School

Social Sciences

Organisational unit: School

1 shared research output

Chemistry

Engineering and Physical Sciences

Organisational unit: School

1 shared research output

Centre for Endocrinology, Diabetes and Metabolism

Metabolism and Systems Research

Organisational unit: Centre

1 shared research output

Microbiology and Infection

Medical and Dental Sciences

Organisational unit: School

1 shared research output

Engineering

Engineering and Physical Sciences

Organisational unit: School

1 shared research output

Economics

Birmingham Business School

Organisational unit: Department

1 shared research output

Birmingham Clinical Trials Unit

Applied Health Research

Organisational unit: Department

1 shared research output

Cancer Clinical Trials Unit

Cancer and Genomic Sciences

Organisational unit: Department

1 shared research output

Queen Elizabeth Hospital Birmingham

External organisation: Unknown

21 shared research output

University Hospital Birmingham NHS Foundation Trust

External organisation: Health-related organisation

20 shared research output

University of Birmingham

External organisation: University or other Higher Education Institute

20 shared research output

University of Oxford

External organisation: University or other Higher Education Institute

9 shared research output

Imperial College London

External organisation: University or other Higher Education Institute

9 shared research output

University of Nottingham

External organisation: University or other Higher Education Institute

7 shared research output

University College London

External organisation: University or other Higher Education Institute

6 shared research output

Newcastle University

External organisation: University or other Higher Education Institute

5 shared research output

University of Cambridge

External organisation: University or other Higher Education Institute

4 shared research output

University of Southampton

External organisation: University or other Higher Education Institute

3 shared research output

Health Data Research UK

External organisation: Other

3 shared research output

Queen Elizabeth Hospital

External organisation: Unknown

3 shared research output

University of Leicester

External organisation: University or other Higher Education Institute

2 shared research output

Google, Inc.

External organisation: Unknown

2 shared research output

University of Toronto

External organisation: University or other Higher Education Institute

2 shared research output

King Saud University

External organisation: University or other Higher Education Institute

2 shared research output

Royal Brompton and Harefield NHS Trust

External organisation: Medical

2 shared research output

Leeds Teaching Hospitals NHS Trust

External organisation: Health-related organisation

2 shared research output

University of Adelaide

External organisation: University or other Higher Education Institute

2 shared research output

University of Newcastle

External organisation: University or other Higher Education Institute

2 shared research output

Institute for Inflammation and Ageing

External organisation: Unknown

2 shared research output

Linköping University

External organisation: University or other Higher Education Institute

2 shared research output

Swansea University

External organisation: University or other Higher Education Institute

2 shared research output

Oxford University Hospitals NHS Foundation Trust

External organisation: Health-related organisation

2 shared research output

King Saud bin Abdulaziz University for Health Sciences

External organisation: University or other Higher Education Institute

2 shared research output

Massachusetts Institute of Technology

External organisation: University or other Higher Education Institute

2 shared research output

Newcastle upon Tyne Hospitals NHS Foundation Trust

External organisation: Health-related organisation

2 shared research output

University of Sheffield

External organisation: University or other Higher Education Institute

2 shared research output

University of Leeds

External organisation: University or other Higher Education Institute

2 shared research output

Birmingham Women's and Children's NHS Foundation Trust

External organisation: Health-related organisation

2 shared research output

Wellcome Trust

External organisation: Health-related organisation

1 shared research output

Centre for Endocrinology

External organisation: Unknown

1 shared research output

Aston University

External organisation: University or other Higher Education Institute

1 shared research output

Queen's University, Belfast

External organisation: University or other Higher Education Institute

1 shared research output

Queen Elizabeth Hospital

External organisation: Health-related organisation

1 shared research output

Hardian Health

External organisation: Unknown

1 shared research output

Google Research

External organisation: Unknown

1 shared research output

New Cross Hospital

External organisation: Health-related organisation

1 shared research output

Guy's and St Thomas' NHS Foundation Trust

External organisation: Departments of Health/NHS/Social Care

1 shared research output

NIHR Applied Research Collaboration East Midlands

External organisation: Unknown

1 shared research output

German Center for Diabetes Research (DZD)

External organisation: Unknown

1 shared research output

Respiratory Therapy Department

External organisation: Unknown

1 shared research output

Frimley Health NHS Foundation Trust

External organisation: Unknown

1 shared research output

Cambridge University Hospitals NHS Foundation Trust

External organisation: Health-related organisation

1 shared research output

Lancaster University

External organisation: University or other Higher Education Institute

1 shared research output

University of Bolton

External organisation: University or other Higher Education Institute

1 shared research output

Clinical Practice Research Datalink

External organisation: Unknown

1 shared research output

Asthma + Lung UK

External organisation: Unknown

1 shared research output

Glenfield Hospital

External organisation: Unknown

1 shared research output

Whiston Hospital

External organisation: Unknown

1 shared research output

Hammersmith Hospital

External organisation: Unknown

1 shared research output

PIONEER: HDR-UK Health Data Research Hub for Acute Care

External organisation: Unknown

1 shared research output

London School of Hygiene and Tropical Medicine

External organisation: University or other Higher Education Institute

1 shared research output

West Midlands Ambulance Service Foundation Trust

External organisation: Health-related organisation

1 shared research output

University of Edinburgh

External organisation: University or other Higher Education Institute

1 shared research output

University Hospitals of Derby and Burton NHS Trust

External organisation: Unknown

1 shared research output

University of Dundee

External organisation: University or other Higher Education Institute

1 shared research output

King Saud Bin Abdul Aziz University for Health Sciences

External organisation: University or other Higher Education Institute

1 shared research output

King’s College London

External organisation: University or other Higher Education Institute

1 shared research output

Patient Partner

External organisation: Unknown

1 shared research output

Park Medical Partnership

External organisation: Unknown

1 shared research output

Aparito Limited

External organisation: Unknown

1 shared research output

University of Warwick

External organisation: University or other Higher Education Institute

1 shared research output

South Warwickshire NHS Foundation Trust

External organisation: No award or financial backing

1 shared research output

Eberhard Karls University of Tübingen,

External organisation: University or other Higher Education Institute

1 shared research output

Prince Sultan Military College of Health Sciences

External organisation: University or other Higher Education Institute

1 shared research output

Birmingham Children’s Hospital NHS Foundation Trust

External organisation: Unknown

1 shared research output

Medical Devices Technology International Limited (MDTi)

External organisation: Unknown

1 shared research output

P1vital Products Limited

External organisation: Unknown

1 shared research output

NIHR Southampton BRC

External organisation: Unknown

1 shared research output

Vector Institute

External organisation: Unknown

1 shared research output

University Hospitals of Leicester NHS Trust

External organisation: Health-related organisation

1 shared research output

Moorfields Eye Hospital NHS Foundation Trust, London

External organisation: Health-related organisation

1 shared research output

Midlands Health Data Research UK

External organisation: Unknown

1 shared research output

University of Manchester

External organisation: University or other Higher Education Institute

1 shared research output

Flinders University

External organisation: University or other Higher Education Institute

1 shared research output

Harvard Medical School

External organisation: University or other Higher Education Institute

1 shared research output

Medicines and Healthcare products Regulatory Agency

External organisation: Unknown

1 shared research output

resTORbio

External organisation: Unknown

1 shared research output

Royal Bolton NHS Foundation Trust

External organisation: No HESA Fund Source

1 shared research output

Public Health England

External organisation: Unknown

1 shared research output

Sandwell and West Birmingham Hospitals NHS Trust

External organisation: Medical

1 shared research output

Central and North West London NHS Foundation Trust

External organisation: Unknown

1 shared research output

The Hospital for Sick Children, Toronto, Canada

External organisation: Overseas institution

1 shared research output

National Institute for Health Research

External organisation: Unknown

1 shared research output

Society for Acute Medicine

External organisation: Unknown

1 shared research output

SUNY Downstate Medical Center

External organisation: Unknown

1 shared research output

Birmingham Heartlands Hospital

External organisation: Health-related organisation

1 shared research output

Queen Mary, University of London

External organisation: University or other Higher Education Institute

1 shared research output

Max Planck Institute for Biology of Ageing

External organisation: Unknown

1 shared research output

University College London Hospitals NHS Foundation Trust

External organisation: Health-related organisation

1 shared research output

Genomics England Limited

External organisation: Unknown

1 shared research output

Mumford Pharma Consulting, LLC

External organisation: Unknown

1 shared research output

MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research

External organisation: Unknown

1 shared research output

Peter Gilgan Centre for Research and Learning

External organisation: Unknown

1 shared research output

Long Covid Support, UK

External organisation: Unknown

1 shared research output

Gt. Ormond St. Hospital for Children

External organisation: Unknown

1 shared research output

Insignia Medical Systems Limited

External organisation: Unknown

1 shared research output

University of Birmingham

External organisation: University or other Higher Education Institute

1 shared research output

Patient Representative

External organisation: Unknown

1 shared research output