Christopher Bunce – Network — University of Birmingham

View Scopus Profile

Accepting PhD Students

PhD projects

Chris Bunce directs a translational research group dedicated to the development of novel therapies for leukaemias and lymphomas. A particular focus is the exploitation of drug redeployment strategies using off-patent drugs to provide affordable therapies that can be exploited by all, including the world's poorer nations.

A particular focus in Professor Bunce’s translational leukaemia and lymphoma research is the use of old drugs for new diseases. Drug redeployment endeavours to use relatively cheap available drugs and to use them in new ways. His group's approach is to take drugs that are not considered as anti-cancer drugs and to use them in combinations that generate an anti-cancer effect. The group's most advanced project is the use of the contraceptive drug medroxyprogesterone acetate combined with a cholesterol lowering drug Bezafibrate. This remarkable drug combination is now in clinical trials for the treatment of acute myeloid leukemia here in the UK and for Burkitt lymphoma in Malawi.

Research activity per year

The University of Birmingham

Organisational unit: University

95 shared research output

Life and Environmental Sciences

The University of Birmingham

Organisational unit: College

95 shared research output

Medical and Dental Sciences

The University of Birmingham

Organisational unit: College

89 shared research output

Immunology and Immunotherapy

Medical and Dental Sciences

Organisational unit: School

47 shared research output

Cancer and Genomic Sciences

Medical and Dental Sciences

Organisational unit: School

42 shared research output

Clinical Sciences

Medical and Dental Sciences

Organisational unit: School

32 shared research output

Cancer Clinical Trials Unit

Cancer and Genomic Sciences

Organisational unit: Department

13 shared research output

Birmingham Medical School

Clinical Sciences

Organisational unit: Department

10 shared research output

Inflammation and Ageing

Medical and Dental Sciences

Organisational unit: School

8 shared research output

Biomedical Sciences

Clinical Sciences

Organisational unit: Department

6 shared research output

Arts and Law

The University of Birmingham

Organisational unit: College

5 shared research output

Metabolism and Systems Research

Medical and Dental Sciences

Organisational unit: School

5 shared research output

Pharmacy

Clinical Sciences

Organisational unit: Department

4 shared research output

English, Drama and Creative Studies

Organisational unit: School

4 shared research output

Dentistry

Clinical Sciences

Organisational unit: Department

2 shared research output

Geography, Earth and Environmental Sciences

Life and Environmental Sciences

Organisational unit: School

1 shared research output

Engineering and Physical Sciences

The University of Birmingham

Organisational unit: College

1 shared research output

Birmingham Law School

Organisational unit: School

1 shared research output

Chemistry

Engineering and Physical Sciences

Organisational unit: School

1 shared research output

Centre for Endocrinology, Diabetes and Metabolism

Metabolism and Systems Research

Organisational unit: Centre

1 shared research output

Cardiovascular Sciences

Medical and Dental Sciences

Organisational unit: School

1 shared research output

Education

Social Sciences

Organisational unit: School

1 shared research output

Social Sciences

The University of Birmingham

Organisational unit: College

1 shared research output

Disability, Inclusion and Special Needs

Organisational unit: Department

1 shared research output

Earth and Environmental Sciences

Geography, Earth and Environmental Sciences

Organisational unit: Department

1 shared research output

University of Birmingham

External organisation: University or other Higher Education Institute

5 shared research output

Department of Immunology

External organisation: Unknown

4 shared research output

University of Bath

External organisation: University or other Higher Education Institute

2 shared research output

Department of Biochemistry

External organisation: Unknown

2 shared research output

Aston University

External organisation: University or other Higher Education Institute

1 shared research output

CCRIS

External organisation: Unknown

1 shared research output

Universiti Kebangsaan

External organisation: University or other Higher Education Institute

1 shared research output

Liverpool John Moores University

External organisation: University or other Higher Education Institute

1 shared research output

General Hospital

External organisation: Unknown

1 shared research output

Sch. Biochem. Ctr. Clin. Res. I.

External organisation: Unknown

1 shared research output

University Hospitals Coventry and Warwickshire NHS Trust

External organisation: Health-related organisation

1 shared research output

Roswell Park Cancer Institute

External organisation: No HESA Fund Source

1 shared research output

University of East Anglia

External organisation: University or other Higher Education Institute

1 shared research output

Chester Medical School

External organisation: Unknown

1 shared research output

King’s College London

External organisation: University or other Higher Education Institute

1 shared research output

Helmholtz Center for Environmental Research

External organisation: University or other Higher Education Institute

1 shared research output

University of Oxford

External organisation: University or other Higher Education Institute

1 shared research output

AstraZeneca

External organisation: Health-related organisation

1 shared research output

University of Liverpool

External organisation: University or other Higher Education Institute

1 shared research output

The Royal Orthopaedic Hospital NHS Foundation Trust

External organisation: Medical

1 shared research output

University of Manchester

External organisation: University or other Higher Education Institute

1 shared research output

University of Chester

External organisation: University or other Higher Education Institute

1 shared research output

University of Cambridge

External organisation: University or other Higher Education Institute

1 shared research output

Università degli Studi di Milano

External organisation: University or other Higher Education Institute

1 shared research output

Molecular Histology and Cell Growth Unit, INGM - Fondazione Istituto Nazionale Genetica Molecolare

External organisation: Unknown

1 shared research output

Queen Elizabeth Hospital Birmingham

External organisation: Unknown

1 shared research output

Royal Wolverhampton Hospitals NHS Trust

External organisation: Medical

1 shared research output

University of Leeds

External organisation: University or other Higher Education Institute

1 shared research output

Pennington Biomedical Research Center

External organisation: Health-related organisation

1 shared research output

Roswell Park Cancer Institute,, NY 14263, USA

External organisation: No HESA Fund Source

1 shared research output

Department of Paediatrics, College of Medicine, Queen Elizabeth Central Hospital, Blantyre, Malawi.

External organisation: Unknown

1 shared research output

Department of Haematology

External organisation: Unknown

1 shared research output