Abstract
This commentary revisits a paper from Clinical Science in 1972 entitled “The distribution and storage of vitamin D and its metabolites in human tissues” by Barbara Mawer, Bill Stanbury and colleagues. The paper continues to be well cited 50 years later, in part because the study it describes – which includes the use of human autopsy tissue – would be difficult to replicate today. However, the paper also has resonance today because the focus of the study – what is the fate of vitamin D in the body? – is still not clear. This commentary discusses why the Mawer et al. study was a major advance when published and why there is still much to be learned from this paper half a century later.
Original language | English |
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Pages (from-to) | 639-642 |
Number of pages | 4 |
Journal | Clinical Science |
Volume | 136 |
Issue number | 8 |
DOIs | |
Publication status | Published - 27 Apr 2022 |
Keywords
- 25-hydroxyvitamin D
- adipose
- bile
- cholecalciferol
- metabolism