Doxorubicin encapsulated hollow self-assembled CuS nanoparticles clusters for bio-responsive chemo-photo therapy

Swaroop Chakraborty; Rajendra Prasad; Pramina Kumari Pandey; Amreen Khan; Nishant Kumar Jain; Eugenia Valsami Jones; Rohit Srivastava; Superb K. Misra

doi:10.1016/j.matlet.2022.133017

Doxorubicin encapsulated hollow self-assembled CuS nanoparticles clusters for bio-responsive chemo-photo therapy

Swaroop Chakraborty, Rajendra Prasad, Pramina Kumari Pandey, Amreen Khan, Nishant Kumar Jain, Eugenia Valsami Jones, Rohit Srivastava, Superb K. Misra

Earth and Environmental Sciences

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Abstract

Herein, we reported self-assembled highly dispersed hollow CuS nanoparticle clusters (CuS NC) with promising photothermal efficiency of 40.5 %, uniform particle size distribution (∼150 nm), porosity and exhibiting high biocompatibility. Further, these designed photothermal hybrid structures are engineered with Doxorubicin anticancer drug molecules (DOX@CuS NC) for bio-responsive chemo-photo therapy of breast cancer (>70 % cell death at a concentration of 20 µg mL ⁻¹).

Original language	English
Article number	133017
Number of pages	4
Journal	Materials Letters
Volume	327
Early online date	17 Aug 2022
DOIs	https://doi.org/10.1016/j.matlet.2022.133017
Publication status	Published - 15 Nov 2022

Bibliographical note

Funding Information:
This work has been financially supported by IMPRINT (Project No. 6408, MHRD), and SERB-CRG (CRG/2019/006165). he authors would like to acknowledge the equipment support provided by DST-FIST through SR/FST/ET-I/2017/18.

Publisher Copyright:
© 2022 The Author(s)

Keywords

Chemotherapy
CuS nanoparticles
Doxorubicin
Photothermal therapy
Self-assembled clusters

ASJC Scopus subject areas

General Materials Science
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering

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10.1016/j.matlet.2022.133017Licence: Creative Commons: Attribution (CC BY)

ChakrabortyS2022DoxorubicinFinal published version, 6.01 MBLicence: Creative Commons: Attribution (CC BY)

Cite this

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title = "Doxorubicin encapsulated hollow self-assembled CuS nanoparticles clusters for bio-responsive chemo-photo therapy",

abstract = "Herein, we reported self-assembled highly dispersed hollow CuS nanoparticle clusters (CuS NC) with promising photothermal efficiency of 40.5 %, uniform particle size distribution (∼150 nm), porosity and exhibiting high biocompatibility. Further, these designed photothermal hybrid structures are engineered with Doxorubicin anticancer drug molecules (DOX@CuS NC) for bio-responsive chemo-photo therapy of breast cancer (>70 % cell death at a concentration of 20 µg mL −1).",

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note = "Funding Information: This work has been financially supported by IMPRINT (Project No. 6408, MHRD), and SERB-CRG (CRG/2019/006165). he authors would like to acknowledge the equipment support provided by DST-FIST through SR/FST/ET-I/2017/18. Publisher Copyright: {\textcopyright} 2022 The Author(s)",

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doi = "10.1016/j.matlet.2022.133017",

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T1 - Doxorubicin encapsulated hollow self-assembled CuS nanoparticles clusters for bio-responsive chemo-photo therapy

AU - Chakraborty, Swaroop

AU - Prasad, Rajendra

AU - Pandey, Pramina Kumari

AU - Khan, Amreen

AU - Jain, Nishant Kumar

AU - Jones, Eugenia Valsami

AU - Srivastava, Rohit

AU - Misra, Superb K.

N1 - Funding Information: This work has been financially supported by IMPRINT (Project No. 6408, MHRD), and SERB-CRG (CRG/2019/006165). he authors would like to acknowledge the equipment support provided by DST-FIST through SR/FST/ET-I/2017/18. Publisher Copyright: © 2022 The Author(s)

PY - 2022/11/15

Y1 - 2022/11/15

N2 - Herein, we reported self-assembled highly dispersed hollow CuS nanoparticle clusters (CuS NC) with promising photothermal efficiency of 40.5 %, uniform particle size distribution (∼150 nm), porosity and exhibiting high biocompatibility. Further, these designed photothermal hybrid structures are engineered with Doxorubicin anticancer drug molecules (DOX@CuS NC) for bio-responsive chemo-photo therapy of breast cancer (>70 % cell death at a concentration of 20 µg mL −1).

AB - Herein, we reported self-assembled highly dispersed hollow CuS nanoparticle clusters (CuS NC) with promising photothermal efficiency of 40.5 %, uniform particle size distribution (∼150 nm), porosity and exhibiting high biocompatibility. Further, these designed photothermal hybrid structures are engineered with Doxorubicin anticancer drug molecules (DOX@CuS NC) for bio-responsive chemo-photo therapy of breast cancer (>70 % cell death at a concentration of 20 µg mL −1).

KW - Chemotherapy

KW - CuS nanoparticles

KW - Doxorubicin

KW - Photothermal therapy

KW - Self-assembled clusters

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U2 - 10.1016/j.matlet.2022.133017

DO - 10.1016/j.matlet.2022.133017

M3 - Article

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JO - Materials Letters

JF - Materials Letters

M1 - 133017

ER -

Doxorubicin encapsulated hollow self-assembled CuS nanoparticles clusters for bio-responsive chemo-photo therapy

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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