Temperature dependent hyperspectral terahertz imaging of human bone for disease diagnosis

Suzanna Freer; Cong Sui; Liam M. Grover; S. M. Hanham; Miguel Navarro-Cia

doi:10.1117/12.2610249

Temperature dependent hyperspectral terahertz imaging of human bone for disease diagnosis

Suzanna Freer, Cong Sui, Liam M. Grover, S. M. Hanham, Miguel Navarro-Cia

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Water is a fundamental component of many biological systems. The ability to detect water therefore provides great insight into system functionality, particularly in the development of disease. In this work, the high interaction of terahertz radiation with water, paired with the dependence of the dynamics of water molecules with varying temperature, is utilised to monitor changes in the composition of bone tissue. Heterotopic ossification (HO) bone samples and deionised free water are measured using terahertz time-domain spectroscopy for varying environmental temperatures, for prospective use in disease diagnosis.

Original language	English
Title of host publication	Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX
Editors	Caroline Boudoux
Publisher	SPIE
ISBN (Electronic)	9781510647701
ISBN (Print)	9781510647695
DOIs	https://doi.org/10.1117/12.2610249
Publication status	Published - 7 Mar 2022
Event	SPIE BIOS: Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX - San Francisco, United States Duration: 23 Jan 2022 → 24 Jan 2022

Publication series

Name	Progress in biomedical optics and imaging
Publisher	SPIE
Volume	11949
ISSN (Print)	1605-7422
ISSN (Electronic)	2410-9045

Conference

Conference	SPIE BIOS
Country/Territory	United States
City	San Francisco
Period	23/01/22 → 24/01/22

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1117/12.2610249

Cite this

Freer, S., Sui, C., Grover, L. M., Hanham, S. M., & Navarro-Cia, M. (2022). Temperature dependent hyperspectral terahertz imaging of human bone for disease diagnosis. In C. Boudoux (Ed.), Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX Article 1194904 (Progress in biomedical optics and imaging; Vol. 11949). SPIE. https://doi.org/10.1117/12.2610249

@inproceedings{c81877e80e76491bb13dfbd45aa8eb16,

title = "Temperature dependent hyperspectral terahertz imaging of human bone for disease diagnosis",

abstract = "Water is a fundamental component of many biological systems. The ability to detect water therefore provides great insight into system functionality, particularly in the development of disease. In this work, the high interaction of terahertz radiation with water, paired with the dependence of the dynamics of water molecules with varying temperature, is utilised to monitor changes in the composition of bone tissue. Heterotopic ossification (HO) bone samples and deionised free water are measured using terahertz time-domain spectroscopy for varying environmental temperatures, for prospective use in disease diagnosis.",

author = "Suzanna Freer and Cong Sui and Grover, {Liam M.} and Hanham, {S. M.} and Miguel Navarro-Cia",

year = "2022",

month = mar,

day = "7",

doi = "10.1117/12.2610249",

language = "English",

isbn = "9781510647695",

series = "Progress in biomedical optics and imaging",

publisher = "SPIE",

editor = "{Boudoux }, Caroline",

booktitle = "Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX",

note = "SPIE BIOS : Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX ; Conference date: 23-01-2022 Through 24-01-2022",

}

Freer, S, Sui, C , Grover, LM , Hanham, SM & Navarro-Cia, M 2022, Temperature dependent hyperspectral terahertz imaging of human bone for disease diagnosis. in C Boudoux (ed.), Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX., 1194904, Progress in biomedical optics and imaging, vol. 11949, SPIE, SPIE BIOS, San Francisco, California, United States, 23/01/22. https://doi.org/10.1117/12.2610249

Temperature dependent hyperspectral terahertz imaging of human bone for disease diagnosis. / Freer, Suzanna; Sui, Cong ; Grover, Liam M. et al.
Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX. ed. / Caroline Boudoux . SPIE, 2022. 1194904 (Progress in biomedical optics and imaging; Vol. 11949).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Temperature dependent hyperspectral terahertz imaging of human bone for disease diagnosis

AU - Freer, Suzanna

AU - Sui, Cong

AU - Grover, Liam M.

AU - Hanham, S. M.

AU - Navarro-Cia, Miguel

PY - 2022/3/7

Y1 - 2022/3/7

N2 - Water is a fundamental component of many biological systems. The ability to detect water therefore provides great insight into system functionality, particularly in the development of disease. In this work, the high interaction of terahertz radiation with water, paired with the dependence of the dynamics of water molecules with varying temperature, is utilised to monitor changes in the composition of bone tissue. Heterotopic ossification (HO) bone samples and deionised free water are measured using terahertz time-domain spectroscopy for varying environmental temperatures, for prospective use in disease diagnosis.

AB - Water is a fundamental component of many biological systems. The ability to detect water therefore provides great insight into system functionality, particularly in the development of disease. In this work, the high interaction of terahertz radiation with water, paired with the dependence of the dynamics of water molecules with varying temperature, is utilised to monitor changes in the composition of bone tissue. Heterotopic ossification (HO) bone samples and deionised free water are measured using terahertz time-domain spectroscopy for varying environmental temperatures, for prospective use in disease diagnosis.

U2 - 10.1117/12.2610249

DO - 10.1117/12.2610249

M3 - Conference contribution

SN - 9781510647695

T3 - Progress in biomedical optics and imaging

BT - Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX

A2 - Boudoux , Caroline

PB - SPIE

T2 - SPIE BIOS

Y2 - 23 January 2022 through 24 January 2022

ER -

Temperature dependent hyperspectral terahertz imaging of human bone for disease diagnosis

Abstract

Publication series

Conference

UN SDGs

Access to Document

Fingerprint

Cite this