TY - JOUR
T1 - The Clinical Relevance of Autonomic Dysfunction, Cerebral Hemodynamics and Sleep Interactions in Individuals Living with SCI
AU - Ji, Wenjie
AU - Nightingale, Tom E.
AU - Zhao, Fei
AU - Fritz, Nora E.
AU - Phillips, Aaron A.
AU - Sisto, Sue Ann
AU - Nash, Mark S.
AU - Badr, M.Safwan
AU - Wecht, Jill M.
AU - Mateika, Jason H.
AU - Panza, Gino S.
PY - 2023/8/23
Y1 - 2023/8/23
N2 - A myriad of physiological impairments is seen in individuals following a spinal cord injury (SCI). These include altered autonomic function, cerebral hemodynamics, and sleep. These physiological systems are interconnected and likely insidiously interact leading to secondary complications. These impairments negatively influence quality of life. A comprehensive review of these systems, and their interplay, may improve clinical treatment and the rehabilitation plan of individuals living with SCI. Thus, these physiological measures should receive more clinical consideration. This special communication introduces the under investigated autonomic dysfunction, cerebral hemodynamics, and sleep disorders in people with SCI to stakeholders involved in SCI rehabilitation. We also discuss the linkage between autonomic dysfunction, cerebral hemodynamics, and sleep disorders and some secondary outcomes are discussed. Recent evidence is synthesized to make clinical recommendations on the assessment and potential management of important autonomic, cerebral hemodynamics, and sleep-related dysfunction in people with SCI. Finally, a few recommendations for clinicians and researchers are provided.
AB - A myriad of physiological impairments is seen in individuals following a spinal cord injury (SCI). These include altered autonomic function, cerebral hemodynamics, and sleep. These physiological systems are interconnected and likely insidiously interact leading to secondary complications. These impairments negatively influence quality of life. A comprehensive review of these systems, and their interplay, may improve clinical treatment and the rehabilitation plan of individuals living with SCI. Thus, these physiological measures should receive more clinical consideration. This special communication introduces the under investigated autonomic dysfunction, cerebral hemodynamics, and sleep disorders in people with SCI to stakeholders involved in SCI rehabilitation. We also discuss the linkage between autonomic dysfunction, cerebral hemodynamics, and sleep disorders and some secondary outcomes are discussed. Recent evidence is synthesized to make clinical recommendations on the assessment and potential management of important autonomic, cerebral hemodynamics, and sleep-related dysfunction in people with SCI. Finally, a few recommendations for clinicians and researchers are provided.
U2 - 10.1016/j.apmr.2023.08.006
DO - 10.1016/j.apmr.2023.08.006
M3 - Article
SN - 0003-9993
JO - Archives of Physical Medicine and Rehabilitation
JF - Archives of Physical Medicine and Rehabilitation
ER -