Extended semen examinations in the sixth edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen: contributing to the understanding of the function of the male reproductive system

Elisabetta Baldi; Meurig Thomas Gallagher; Stepan Krasnyak; Jackson Kirkman-Brown; Editorial Board members of the World Health Organization laboratory manual for the examination and processing of human semen

doi:10.1016/j.fertnstert.2021.11.034

Extended semen examinations in the sixth edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen: contributing to the understanding of the function of the male reproductive system

Elisabetta Baldi, Meurig Thomas Gallagher, Stepan Krasnyak, Jackson Kirkman-Brown, Editorial Board members of the World Health Organization laboratory manual for the examination and processing of human semen

Metabolism and Systems Research

Research output: Contribution to journal › Review article › peer-review

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Abstract

In the sixth edition of the World Health Organization manual for the examination and processing of human semen, extended examination methods to provide key diagnostics in the investigation of the male reproductive system function are elaborated. These go beyond the basic analysis of semen and may be useful in more specifically guiding the clinical characterization of fertile or infertile men. Among the extended examinations included in the chapter, the use of multiparametric scoring for sperm morphological defects, sperm DNA fragmentation, and the roles for computer-assisted analysis of sperm or semen are arguably those that will be the most widely used and may also cause the most debate.

Original language	English
Pages (from-to)	252-257
Number of pages	6
Journal	Fertility and Sterility
Volume	117
Issue number	2
Early online date	3 Jan 2022
DOIs	https://doi.org/10.1016/j.fertnstert.2021.11.034
Publication status	Published - 1 Mar 2022

Bibliographical note

Funding Information:
The development of the “sixth edition of World Health Organization (WHO) laboratory manual for the examination and processing of human semen” was funded by the UNDP-UNFPA-UNICEF-WHO-World Bank Special Programme of Research, Development and Research Training in Human Reproduction, a cosponsored programme executed by WHO.

Keywords

fertility
infertility
world health organisation
semen analysis
male reproduction
CASA
sperm motility
sperm DNA
Multiparametric

ASJC Scopus subject areas

Obstetrics and Gynaecology
Reproductive Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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BaldiE2022ExtendedAccepted author manuscript, 247 KBLicence: Creative Commons: Attribution-NonCommercial-NoDerivs (CC BY-NC-ND)

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Baldi, E., Gallagher, M. T., Krasnyak, S., Kirkman-Brown, J., & Editorial Board members of the World Health Organization laboratory manual for the examination and processing of human semen (2022). Extended semen examinations in the sixth edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen: contributing to the understanding of the function of the male reproductive system. Fertility and Sterility, 117(2), 252-257. Advance online publication. https://doi.org/10.1016/j.fertnstert.2021.11.034

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Baldi, E, Gallagher, MT, Krasnyak, S, Kirkman-Brown, J & Editorial Board members of the World Health Organization laboratory manual for the examination and processing of human semen 2022, 'Extended semen examinations in the sixth edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen: contributing to the understanding of the function of the male reproductive system', Fertility and Sterility, vol. 117, no. 2, pp. 252-257. https://doi.org/10.1016/j.fertnstert.2021.11.034

Extended semen examinations in the sixth edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen: contributing to the understanding of the function of the male reproductive system. / Baldi, Elisabetta; Gallagher, Meurig Thomas; Krasnyak, Stepan et al.
In: Fertility and Sterility, Vol. 117, No. 2, 01.03.2022, p. 252-257.

Research output: Contribution to journal › Review article › peer-review

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Baldi E, Gallagher MT, Krasnyak S, Kirkman-Brown J, Editorial Board members of the World Health Organization laboratory manual for the examination and processing of human semen. Extended semen examinations in the sixth edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen: contributing to the understanding of the function of the male reproductive system. Fertility and Sterility. 2022 Mar 1;117(2):252-257. Epub 2022 Jan 3. doi: 10.1016/j.fertnstert.2021.11.034