Image Analysis and Deep Learning Web Services for Nano informatics

Anastasios G. Papadiamantis, Antreas Afantitis, Andreas Tsoumanis, Pantelis Karatzas, Philip Doganis, Dimitra Danai Varsou, Haralambos Sarimveis, Laura Bradford, Eugenia Valsami-Jones, Iseult Lynch, Georgia Melagraki

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

In this chapter, we present and discuss the state of the art in image analysis tools for nanomaterials’ toxicology. These tools employ novel computational techniques and can contribute to the in silico characterization of materials in complex matrices and their toxicity assessment, by way of recognizing malformations in Daphnia magna. The tools presented were developed using well-established computational platforms and complemented with an user-friendly interface to allow even users without no informatics background to easily get acquainted with them and facilitating their routine use. The tools are freely available as cloud web-applications, while it is also possible to use Application Programming Interfaces (APIs) to integrate the tools into external platforms or to download a containerized Docker application for local deployment. By the end of the chapter, readers will have a clear overview of the functionalities and abilities of the presented tools and the potential added value they offer in terms of working hours, experimental cost, and research outputs for in silico evaluation of nanomaterials toxicity as part of an integrated approach to testing and assessment.

Original languageEnglish
Title of host publicationChemometrics and Cheminformatics in Aquatic Toxicology
EditorsKunal Roy
PublisherWiley
Chapter28
Pages547-564
Number of pages18
ISBN (Electronic)9781119681397, 9781119681601
ISBN (Print)9781119681595
DOIs
Publication statusPublished - Jan 2022

Bibliographical note

Publisher Copyright:
© 2022 John Wiley and Sons, Inc.

Keywords

  • artificial intelligence
  • cheminformatics
  • Daphnia magna
  • deep learning
  • DeepDaph
  • ecotoxicology
  • Enalos Cloud Platform
  • engineered nanomaterials
  • image analysis
  • nanoinformatics
  • NanoXtract

ASJC Scopus subject areas

  • General Chemistry
  • Pharmacology, Toxicology and Pharmaceutics(all)

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