Acoustic bubble dynamics in a microvessel surrounded by elastic material

This paper is concerned with microbubble dynamics in a blood vessel surrounded by elastic tissue subject to ultrasound, which are associated with important applications in medical ultrasonics. Both the blood flow inside the vessel and the tissue flow external to the vessel are modeled using the potential flow theory coupled with the boundary element method. The elasticity of tissue is modeled through the inclusion of a pressure term in the dynamic boundary condition at the interface between the two fluids. Weakly viscous effects are considered using viscous potential flow theory. The numerical model is validated by comparison with the theoretical results of the Rayleigh-Plesset equation for spherical bubbles, the numerical results for acoustic bubbles in an unbounded flow, and the experimental images for a spark generated bubble in a rigid circular cylinder. Numerical analyses are then performed for the bubble oscillation, jet formation and penetration through the bubble, and the deformation of the vessel wall in terms of the ultrasound amplitude and the vessel radius.