TY - JOUR
T1 - Effects of aging on resting metabolic rate
T2 - A systematic review and meta-analysis
AU - Júnior, Paulo Roberto Hernandes
AU - Brandão, Bruno Carvalho
AU - de Abreu Cunha Lopes, Patrick
AU - Veiga Sardeli, Amanda
AU - de Resende Côrtes , Paula Pitta
PY - 2021/8/20
Y1 - 2021/8/20
N2 - Objective. To meta-analyze previous literature in order to find a consensus regarding aging effects on resting metabolic rate (RMR) and to identify the main players in this process. Methods. Through a search on PubMed eighteen trials comparing RMR between older and young adults were included for meta-analysis. Results. Older adults had significantly lower RMR than young adults (-437 kJ/d [-591; 283], p<0.001). While older men had a reduction of -725 kJ/d ([-1068; -382], p<0.001), older women had just less than half of this reduction (-233 kJ/d [ -308; -158], p<0.001). The age induced-RMR reduction was predicted by muscle mass difference between groups (r2=0.55), but not by body mass or other body composition components. Conclusion. RMR is indeed reduced in older adults and muscle mass loss is the main player in this process. Future studies should investigate how much of this reduction can account for poor health conditions in older adults.
AB - Objective. To meta-analyze previous literature in order to find a consensus regarding aging effects on resting metabolic rate (RMR) and to identify the main players in this process. Methods. Through a search on PubMed eighteen trials comparing RMR between older and young adults were included for meta-analysis. Results. Older adults had significantly lower RMR than young adults (-437 kJ/d [-591; 283], p<0.001). While older men had a reduction of -725 kJ/d ([-1068; -382], p<0.001), older women had just less than half of this reduction (-233 kJ/d [ -308; -158], p<0.001). The age induced-RMR reduction was predicted by muscle mass difference between groups (r2=0.55), but not by body mass or other body composition components. Conclusion. RMR is indeed reduced in older adults and muscle mass loss is the main player in this process. Future studies should investigate how much of this reduction can account for poor health conditions in older adults.
KW - Calorimetry
KW - Metabolism
KW - Aging
KW - Health
KW - Resting metabolic Rate
U2 - 10.34119/bjhrv4n4-266
DO - 10.34119/bjhrv4n4-266
M3 - Article
SN - 2595-6825
VL - 4
SP - 17867
EP - 17882
JO - Brazilian Journal of Health Review
JF - Brazilian Journal of Health Review
IS - 4
ER -