Abstract
Disorder of consciousness (DoC) after severe brain injury presents numerous challenges to clinicians, as the diagnosis, prognosis, and management are often uncertain. Magnetic resonance imaging (MRI) has long been used to evaluate brain structure in patients with DoC. More recently, advances in MRI technology have permitted more detailed investigations of the brain's structural integrity (via diffusion MRI) and function (via functional MRI). A growing literature has begun to show that these advanced forms of MRI may improve our understanding of DoC pathophysiology, facilitate the identification of patient consciousness, and improve the accuracy of clinical prognostication. Here we review the emerging evidence for the application of advanced MRI for patients with DoC.
| Original language | English |
|---|---|
| Pages (from-to) | 325-334 |
| Number of pages | 10 |
| Journal | Seminars in neurology |
| Volume | 42 |
| Issue number | 3 |
| Early online date | 5 Jul 2022 |
| DOIs | |
| Publication status | Published - 13 Sept 2022 |
Bibliographical note
Funding Information:D.F.-E. reports grants or contracts from Medical Research Council (MRC) grant MR/P02596X/1 and Research Collaboration Agreement with HCA Healthcare.
Publisher Copyright:
© 2022 Thieme Medical Publishers, Inc.. All rights reserved.
Keywords
- MRI
- disorders of consciousness
- neuroimaging
- prognostication
- Disorders of consciousness
ASJC Scopus subject areas
- Clinical Neurology
- Neurology