TY - JOUR
T1 - Standardised definitions and diagnostic criteria for extra nodal extension on histopathological examination in head and neck cancer
T2 - HNCIG international consensus recommendations
AU - Abou-Foul, Ahmad
AU - Henson, Christina
AU - Robinson, Max
AU - Chernock, Rebecca D.
AU - Huang, Shao Hui
AU - Lydiatt, William M.
AU - Mcdowell, Lachlan
AU - O'Sullivan, Brian
AU - Perez-Ordonez, Bayardo
AU - Nankivell, Paul
AU - Ruiz-Bravo, Elena
AU - Chiosea, Simion
AU - McGreen, Tina M.
AU - Hunter, Keith D.
AU - Hwang, Jaqueline S. G.
AU - Koljenovic, Senada
AU - Koppes, Sjors A.
AU - Larsen, Stine R.
AU - Lo, Anthony Wi
AU - Costes-Martineau, Valérie
AU - Mittal, Neha
AU - Mori, Toshitaka
AU - Panayiotides, Ioannis G.
AU - Pinto, Clóvis A. L.
AU - Scheckenbach, Kathrin
AU - Seethala, Raja R.
AU - Ulhøi, Benedicte P.
AU - Vingiani, Andrea
AU - Zhang, Yan
AU - Yam, Sue S.
AU - Mehanna, Hisham
N1 - Not yet published as of 22/04/2024.
PY - 2024/3/7
Y1 - 2024/3/7
N2 - Detection of extranodal extension on histopathology (pENE) in surgically treated head and neck squamous cell carcinoma (HNSCC) indicates poor prognosis. However, there is no consensus on the diagnostic criteria, interpretation and reporting pENE, which has contributed to conflicting evidence in the literature, and likely inconsistency clinically. The Head and Neck Cancer International Group conducted a three-round modified Delphi process with a group of 19 international pathology experts, representing 15 national clinical research groups, to generate consensus recommendations for pENE diagnostic criteria. The expert panel achieved strong agreement on terminology and diagnostic features for pENE and soft tissue metastasis. Moreover, the panel reached consensus on reporting of pENE and on nodal sampling.These consensus recommendations, endorsed by 19 organisations representing 34 countries, are a critical development towards more standardised diagnosis and reporting of pENE, and more accurate data collection and analysis.
AB - Detection of extranodal extension on histopathology (pENE) in surgically treated head and neck squamous cell carcinoma (HNSCC) indicates poor prognosis. However, there is no consensus on the diagnostic criteria, interpretation and reporting pENE, which has contributed to conflicting evidence in the literature, and likely inconsistency clinically. The Head and Neck Cancer International Group conducted a three-round modified Delphi process with a group of 19 international pathology experts, representing 15 national clinical research groups, to generate consensus recommendations for pENE diagnostic criteria. The expert panel achieved strong agreement on terminology and diagnostic features for pENE and soft tissue metastasis. Moreover, the panel reached consensus on reporting of pENE and on nodal sampling.These consensus recommendations, endorsed by 19 organisations representing 34 countries, are a critical development towards more standardised diagnosis and reporting of pENE, and more accurate data collection and analysis.
UR - https://www.thelancet.com/journals/lanonc/issue/current
M3 - Article
SN - 1470-2045
JO - The Lancet Oncology
JF - The Lancet Oncology
ER -