The increasing role of structural proteomics in cyanobacteria

Jaspreet k. Sound, Jeddidiah Bellamy-Carter, Aneika c. Leney*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

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Abstract

Cyanobacteria, also known as blue–green algae, are ubiquitous organisms on the planet. They contain tremendous protein machineries that are of interest to the biotechnology industry and beyond. Recently, the number of annotated cyanobacterial genomes has expanded, enabling structural studies on known gene-coded proteins to accelerate. This review focuses on the advances in mass spectrometry (MS) that have enabled structural proteomics studies to be performed on the proteins and protein complexes within cyanobacteria. The review also showcases examples whereby MS has revealed critical mechanistic information behind how these remarkable machines within cyanobacteria function.
Original languageEnglish
Article numberEBC20220095
JournalEssays in Biochemistry
Early online date12 Dec 2022
DOIs
Publication statusE-pub ahead of print - 12 Dec 2022

Keywords

  • Cyanobacteria
  • mass spectrometry
  • post translational modification
  • protein-protein interactions
  • proteomics

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