Alcohol consumption in patients with non-alcoholic fatty liver disease: convenient vs. inconvenient truths

Matthew J Armstrong; Jessica L Mellinger; Palak J Trivedi

doi:10.1038/s41395-018-0237-y

Alcohol consumption in patients with non-alcoholic fatty liver disease: convenient vs. inconvenient truths

Matthew J Armstrong, Jessica L Mellinger, Palak J Trivedi

Immunology and Immunotherapy

Research output: Contribution to journal › Editorial › peer-review

1 Citation (Scopus)

Abstract

Understanding the role of modest alcohol consumption in patients with non-alcohol induced fatty liver disease (NAFLD) remains a significant challenge, with no clear guidance on counselling regarding alcohol use. Conventionally, the strong association of alcohol excess and development of complications related to chronic liver disease, including hepatocellular carcinoma, has led practitioners to advocate complete abstinence to those with NAFLD. New evidence published in this issue of the Red Journal challenges the historic paradigm by showing that modest, non-binge wine consumption (<70 g/week) associates with significantly lower risk of advanced hepatic fibrosis on biopsy compared with complete abstinence across a well-characterised single centre cohort of nearly 200 patients with NAFLD.

Original language	English
Pages (from-to)	1437-1439
Number of pages	3
Journal	The American Journal of Gastroenterology
Volume	113
Issue number	10
DOIs	https://doi.org/10.1038/s41395-018-0237-y
Publication status	Published - Oct 2018

Keywords

Alcohol Drinking
Carcinoma, Hepatocellular
Humans
Liver Cirrhosis
Liver Neoplasms
Non-alcoholic Fatty Liver Disease

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1038/s41395-018-0237-yLicence: None: All rights reserved

Cite this

@article{2f2c71fdaf934a11a0e0efbbcaece0e3,

title = "Alcohol consumption in patients with non-alcoholic fatty liver disease: convenient vs. inconvenient truths",

abstract = "Understanding the role of modest alcohol consumption in patients with non-alcohol induced fatty liver disease (NAFLD) remains a significant challenge, with no clear guidance on counselling regarding alcohol use. Conventionally, the strong association of alcohol excess and development of complications related to chronic liver disease, including hepatocellular carcinoma, has led practitioners to advocate complete abstinence to those with NAFLD. New evidence published in this issue of the Red Journal challenges the historic paradigm by showing that modest, non-binge wine consumption (<70 g/week) associates with significantly lower risk of advanced hepatic fibrosis on biopsy compared with complete abstinence across a well-characterised single centre cohort of nearly 200 patients with NAFLD.",

keywords = "Alcohol Drinking, Carcinoma, Hepatocellular, Humans, Liver Cirrhosis, Liver Neoplasms, Non-alcoholic Fatty Liver Disease",

author = "Armstrong, {Matthew J} and Mellinger, {Jessica L} and Trivedi, {Palak J}",

year = "2018",

month = oct,

doi = "10.1038/s41395-018-0237-y",

language = "English",

volume = "113",

pages = "1437--1439",

journal = "The American Journal of Gastroenterology",

issn = "0002-9270",

publisher = "Nature Publishing Group",

number = "10",

}

TY - JOUR

T1 - Alcohol consumption in patients with non-alcoholic fatty liver disease

T2 - convenient vs. inconvenient truths

AU - Armstrong, Matthew J

AU - Mellinger, Jessica L

AU - Trivedi, Palak J

PY - 2018/10

Y1 - 2018/10

N2 - Understanding the role of modest alcohol consumption in patients with non-alcohol induced fatty liver disease (NAFLD) remains a significant challenge, with no clear guidance on counselling regarding alcohol use. Conventionally, the strong association of alcohol excess and development of complications related to chronic liver disease, including hepatocellular carcinoma, has led practitioners to advocate complete abstinence to those with NAFLD. New evidence published in this issue of the Red Journal challenges the historic paradigm by showing that modest, non-binge wine consumption (<70 g/week) associates with significantly lower risk of advanced hepatic fibrosis on biopsy compared with complete abstinence across a well-characterised single centre cohort of nearly 200 patients with NAFLD.

AB - Understanding the role of modest alcohol consumption in patients with non-alcohol induced fatty liver disease (NAFLD) remains a significant challenge, with no clear guidance on counselling regarding alcohol use. Conventionally, the strong association of alcohol excess and development of complications related to chronic liver disease, including hepatocellular carcinoma, has led practitioners to advocate complete abstinence to those with NAFLD. New evidence published in this issue of the Red Journal challenges the historic paradigm by showing that modest, non-binge wine consumption (<70 g/week) associates with significantly lower risk of advanced hepatic fibrosis on biopsy compared with complete abstinence across a well-characterised single centre cohort of nearly 200 patients with NAFLD.

KW - Alcohol Drinking

KW - Carcinoma, Hepatocellular

KW - Humans

KW - Liver Cirrhosis

KW - Liver Neoplasms

KW - Non-alcoholic Fatty Liver Disease

U2 - 10.1038/s41395-018-0237-y

DO - 10.1038/s41395-018-0237-y

M3 - Editorial

C2 - 30166633

SN - 0002-9270

VL - 113

SP - 1437

EP - 1439

JO - The American Journal of Gastroenterology

JF - The American Journal of Gastroenterology

IS - 10

ER -

Alcohol consumption in patients with non-alcoholic fatty liver disease: convenient vs. inconvenient truths

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this