TY - JOUR
T1 - An Observational Study of Social Interaction Skills and Behaviors in Cornelia de Lange, Fragile X and Rubinstein-Taybi Syndromes
AU - Ellis, Katherine
AU - Oliver, Chris
AU - Stefanidou, Chrysi
AU - Apperly, Ian
AU - Moss, Jo
PY - 2020/3/18
Y1 - 2020/3/18
N2 - We directly assessed the broader aspects of sociability (social enjoyment, social motivation, social interaction skills and social discomfort) in individuals with Cornelia de Lange (CdLS), fragile X (FXS) and Rubinstein-Taybi syndromes (RTS), and their association with autism characteristics and chronological age in these groups. Individuals with FXS (p < 0.01) and RTS (p < 0.01) showed poorer quality of eye contact compared to individuals with CdLS. Individuals with FXS showed less person and more object attention than individuals with CdLS (p < 0.01). Associations between sociability and autism characteristics and chronological age differed between groups, which may indicate divergence in the development and aetiology of different components of sociability across these groups. Findings indicate that individuals with CdLS, FXS and RTS show unique profiles of sociability.
AB - We directly assessed the broader aspects of sociability (social enjoyment, social motivation, social interaction skills and social discomfort) in individuals with Cornelia de Lange (CdLS), fragile X (FXS) and Rubinstein-Taybi syndromes (RTS), and their association with autism characteristics and chronological age in these groups. Individuals with FXS (p < 0.01) and RTS (p < 0.01) showed poorer quality of eye contact compared to individuals with CdLS. Individuals with FXS showed less person and more object attention than individuals with CdLS (p < 0.01). Associations between sociability and autism characteristics and chronological age differed between groups, which may indicate divergence in the development and aetiology of different components of sociability across these groups. Findings indicate that individuals with CdLS, FXS and RTS show unique profiles of sociability.
KW - Eye gaze
KW - Fragile X syndrome
KW - Genetics behavioural
KW - Neurodevelopmental disorders
KW - Social behavior
UR - http://www.scopus.com/inward/record.url?scp=85082848522&partnerID=8YFLogxK
U2 - 10.1007/s10803-020-04440-4
DO - 10.1007/s10803-020-04440-4
M3 - Article
C2 - 32189229
SN - 0162-3257
VL - 50
SP - 4001
EP - 4010
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
IS - 11
ER -