Temperature-dependent dielectric properties of human bone constituents at THz frequencies: contrast mechanisms and bound water dynamics

N Chopra; N. Shaw; L. Lotkowska; C. Sui; J. Lloyd-Hughes

doi:10.1109/IRMMW-THz50927.2022.9896085

Temperature-dependent dielectric properties of human bone constituents at THz frequencies: contrast mechanisms and bound water dynamics

N Chopra, N. Shaw, L. Lotkowska, C. Sui, J. Lloyd-Hughes

Chemical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

THz time domain spectroscopy (THz-TDS) was used to investigate the dielectric properties of constituents of human bone. We report experimental values for refractive index and absorption coefficient for four major anhydrous constituents of bone: Collagen, Hydroxyapatite, Calcite and Amorphous calcium phosphate. We varied the sample temperature in order to explore the physical mechanisms underpinning the THz dielectric function of these constituents. Experimental data were well described using the Debye model for collagen, or the Lorentz model for mineral compounds, respectively. A fitting procedure based on Particle Swarm Optimization was implemented in order to extract the fitting parameters such as relaxation times and oscillator strengths.

Original language	English
Title of host publication	2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz)
Publisher	IEEE
Number of pages	2
ISBN (Electronic)	9781728194271
ISBN (Print)	9781728194288 (PoD)
DOIs	https://doi.org/10.1109/IRMMW-THz50927.2022.9896085
Publication status	Published - 26 Sept 2022
Event	2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz) - Delft, Netherlands Duration: 28 Aug 2022 → 2 Sept 2022

Publication series

Name	International Conference on Infrared, Millimeter, and Terahertz Waves
Publisher	IEEE
ISSN (Print)	2162-2027
ISSN (Electronic)	2162-2035

Conference

Conference	2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz)
Country/Territory	Netherlands
City	Delft
Period	28/08/22 → 2/09/22

Bibliographical note

Acknowledgments:
The authors would like to thank the EPSRC (UK) for funding under grants EP/V047914/1, EP/S018395/1 and the Royal Society under grant IES/R3/183131.

Keywords

Temperature measurement
Spectroscopy
Temperature
Absorption
Fitting
Bones
Data models

Access to Document

10.1109/IRMMW-THz50927.2022.9896085

THEIA: fast super-resolution TeraHErtz mIcroscopy for nAtural Sciences
Navarro-Cia, M.
Engineering & Physical Science Research Council
1/08/19 → 31/03/21
Project: Research

Cite this

Chopra, N., Shaw, N., Lotkowska, L., Sui, C., & Lloyd-Hughes, J. (2022). Temperature-dependent dielectric properties of human bone constituents at THz frequencies: contrast mechanisms and bound water dynamics. In 2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz) Article 9896085 (International Conference on Infrared, Millimeter, and Terahertz Waves). IEEE. https://doi.org/10.1109/IRMMW-THz50927.2022.9896085

@inproceedings{0b828742d2864468911067e056e1d12d,

title = "Temperature-dependent dielectric properties of human bone constituents at THz frequencies: contrast mechanisms and bound water dynamics",

abstract = "THz time domain spectroscopy (THz-TDS) was used to investigate the dielectric properties of constituents of human bone. We report experimental values for refractive index and absorption coefficient for four major anhydrous constituents of bone: Collagen, Hydroxyapatite, Calcite and Amorphous calcium phosphate. We varied the sample temperature in order to explore the physical mechanisms underpinning the THz dielectric function of these constituents. Experimental data were well described using the Debye model for collagen, or the Lorentz model for mineral compounds, respectively. A fitting procedure based on Particle Swarm Optimization was implemented in order to extract the fitting parameters such as relaxation times and oscillator strengths.",

keywords = "Temperature measurement, Spectroscopy, Temperature, Absorption, Fitting, Bones, Data models",

author = "N Chopra and N. Shaw and L. Lotkowska and C. Sui and J. Lloyd-Hughes",

note = "Acknowledgments: The authors would like to thank the EPSRC (UK) for funding under grants EP/V047914/1, EP/S018395/1 and the Royal Society under grant IES/R3/183131.; 2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz) ; Conference date: 28-08-2022 Through 02-09-2022",

year = "2022",

month = sep,

day = "26",

doi = "10.1109/IRMMW-THz50927.2022.9896085",

language = "English",

isbn = "9781728194288 (PoD)",

series = "International Conference on Infrared, Millimeter, and Terahertz Waves",

publisher = "IEEE",

booktitle = "2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz)",

}

Chopra, N, Shaw, N, Lotkowska, L, Sui, C & Lloyd-Hughes, J 2022, Temperature-dependent dielectric properties of human bone constituents at THz frequencies: contrast mechanisms and bound water dynamics. in 2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz)., 9896085, International Conference on Infrared, Millimeter, and Terahertz Waves, IEEE, 2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz), Delft, Netherlands, 28/08/22. https://doi.org/10.1109/IRMMW-THz50927.2022.9896085

Temperature-dependent dielectric properties of human bone constituents at THz frequencies: contrast mechanisms and bound water dynamics. / Chopra, N; Shaw, N.; Lotkowska, L. et al.
2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz). IEEE, 2022. 9896085 (International Conference on Infrared, Millimeter, and Terahertz Waves).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Temperature-dependent dielectric properties of human bone constituents at THz frequencies

T2 - 2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz)

AU - Chopra, N

AU - Shaw, N.

AU - Lotkowska, L.

AU - Sui, C.

AU - Lloyd-Hughes, J.

N1 - Acknowledgments: The authors would like to thank the EPSRC (UK) for funding under grants EP/V047914/1, EP/S018395/1 and the Royal Society under grant IES/R3/183131.

PY - 2022/9/26

Y1 - 2022/9/26

N2 - THz time domain spectroscopy (THz-TDS) was used to investigate the dielectric properties of constituents of human bone. We report experimental values for refractive index and absorption coefficient for four major anhydrous constituents of bone: Collagen, Hydroxyapatite, Calcite and Amorphous calcium phosphate. We varied the sample temperature in order to explore the physical mechanisms underpinning the THz dielectric function of these constituents. Experimental data were well described using the Debye model for collagen, or the Lorentz model for mineral compounds, respectively. A fitting procedure based on Particle Swarm Optimization was implemented in order to extract the fitting parameters such as relaxation times and oscillator strengths.

AB - THz time domain spectroscopy (THz-TDS) was used to investigate the dielectric properties of constituents of human bone. We report experimental values for refractive index and absorption coefficient for four major anhydrous constituents of bone: Collagen, Hydroxyapatite, Calcite and Amorphous calcium phosphate. We varied the sample temperature in order to explore the physical mechanisms underpinning the THz dielectric function of these constituents. Experimental data were well described using the Debye model for collagen, or the Lorentz model for mineral compounds, respectively. A fitting procedure based on Particle Swarm Optimization was implemented in order to extract the fitting parameters such as relaxation times and oscillator strengths.

KW - Temperature measurement

KW - Spectroscopy

KW - Temperature

KW - Absorption

KW - Fitting

KW - Bones

KW - Data models

U2 - 10.1109/IRMMW-THz50927.2022.9896085

DO - 10.1109/IRMMW-THz50927.2022.9896085

M3 - Conference contribution

SN - 9781728194288 (PoD)

T3 - International Conference on Infrared, Millimeter, and Terahertz Waves

BT - 2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz)

PB - IEEE

Y2 - 28 August 2022 through 2 September 2022

ER -

Chopra N, Shaw N, Lotkowska L, Sui C, Lloyd-Hughes J. Temperature-dependent dielectric properties of human bone constituents at THz frequencies: contrast mechanisms and bound water dynamics. In 2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz). IEEE. 2022. 9896085. (International Conference on Infrared, Millimeter, and Terahertz Waves). doi: 10.1109/IRMMW-THz50927.2022.9896085

Temperature-dependent dielectric properties of human bone constituents at THz frequencies: contrast mechanisms and bound water dynamics

Abstract

Publication series

Conference

Bibliographical note

Keywords

Access to Document

Fingerprint

Projects

THEIA: fast super-resolution TeraHErtz mIcroscopy for nAtural Sciences

Cite this